The Influence Of Hypothyroidism For Gynecologic Perioperative Period

Objective: to study the combination of hypothyroidism gynecologicalperioperative influence, reveal mild hypothyroidism can prolong theperioperative peristalsis recovery time, and aggravating electrolytes distur-bance.Methods: patients with prospective observational of125cases, are all inSeptember2010to September2011jilin university hospital of gynecologicalthe inpatient department with the second. Aged17to81years old.Hyperthyroidism in2cases, for sample number2cases less has been removed.According to patients serum TSH (thyroid-stimulating hormone) value caseswill be divided into two groups.(1) quartile TSH2.5mU/L group(Hypothyroidism group59patients);(2)0.3mU/L <TSH <2.5mU/L group(the thyroid normal group, the control group64cases); Two groups of womenin strict rule out always thyroid medical history, history of the hypothalamus,the pituitary disease, chronic heart, liver, kidney disease history andautoimmune diseases and so on. All patients were not use the impact ofelectrolyte metabolism drugs. Each group were statistics serum thyroidhormone levels, and compare postoperative exhaust time, gynecological bowelperistalsis recovery time, time and serum electrolyte changes.Results:1. Hypothyroidism group and in the normal control group opensurgery postoperative exhaust time, defecate time, bowel sounds soundrecovery time, potassium, calcium ions with4days after admissionconcentration of the values of the lower comparison:40-81years oldHypothyroidism group began defecate time was significantly longer thannormal control group, and the differences are statistically significant (P <0.05);40-81years old Hypothyroidism group began potassium ions, and calcium ion concentration and admission potassium, calcium ion concentration differencecompared with normal control group reduced significantly, and have a statisticsdifference (P <0.001).2. Hypothyroidism group and in the normal controlgroup laparoscopic surgery postoperative exhaust time, defecate time, bowelsounds sound recovery time, admission potassium, calcium ions andpostoperative day4concentration lower value comparison:17~40years ofage Hypothyroidism group of laparoscopic surgery, and exhaust time time,sound than normal bowel sounds recovery time was significantly extend, have astatistics difference (P <0.05);17~40years of age Hypothyroidism groupand laparoscopic surgery normal control group4days and admission potassium,calcium ion concentration significantly compared to extend, have a statisticsdifference (P <0.001); Above40years old age Hypothyroidism group andnormal control group only after laparoscopic4days and admission potassium,calcium ion concentration significantly lower than, have a statistics difference(P <0.05).3. Hypothyroidism group and in the normal control grouplaparoscopic ovarian benign tumor postoperative exhaust time, defecate time,bowel sounds sound recovery time, admission potassium, calcium ions andpostoperative day4potassium, calcium ion concentration lower valuecomparison: Hypothyroidism group ovarian benign tumor laparoscopic surgeryexhaust time than normal control group significantly extend, have a statisticsdifference (P <0.05); Hypothyroidism group and in the normal control groupovarian benign tumor laparoscopic postoperative day4and admissionpotassium, calcium ion concentration significantly prolonged compared withstatistical difference (P <0.001).4. Different TSH level grouping laparoscopicsurgery under group exhaust time, defecate time, bowel sounds sound recoverytime, with4days after admission potassium, calcium ion concentration oflower value is:(1) TSH0.3~2.5mU/L group and TSH2.5~5.6mU/L groupcompared: TSH2.5~5.6mU/L group than in the TSH0.3~2.5mU/L group defecate time delay, serum potassium, calcium ion reduce apparent, have astatistics difference (P <0.05).(2) the TSH0.3~2.5mU/L group and TSH>5.6mU/L group compared: TSH>5.6mU/L group than in the TSH0.3~2.5mU/L group than in the defecate time delay, serum potassium, calcium ionreduce obviously, have a statistics difference (P <0.05).Conclusion:1, merger hypothyroidism influence the endoderm functionexpression.2, merger hypothyroidism influence of gynecological diseasespostoperative peristalsis function recovery.3, whether it JiaJian or the clinicalJiaJian clinical, serum TSH is the most main index of the diagnosis.