| Objective (1) Observing and measuring the segment of the internal carotid arteryand siphon shape.(2) Comparing the calcification distribution of Carotid and SiphonSegment of Internal Carotid Artery between normal group and sclerosis group.（3）Imitating the normal character of hemodynamic the normal Carotidand Siphon Segment of Internal Carotid Artery, and the change of hemodynamic afterAtherosclerotic Plaque, comparing the two for the research of the relationshipbetween the hemodynamic and siphon hardening.Methods （1）requirement of the object of study: patients aged above50,who had CTAneck inspection in this hospital from January2011to December2011. All patientsdivided into2groups: the normal group and the sclerosis group with70each. Rebuildthe Siphon department blood vessels, observing the form of blood vessel,andmeasuring the break angle of C4、C5,and the diameter of blood vessel, to get thedifference of the two.（2）To have finite element modeling on the basis of the CAT data, imitatingSiphon department hemodynamic with ANSYS13.0CFX software. Observing thenormal blood flow and the change caused by Stiffblood vessels, analysing the effect tothe atherosclerosis.Results （1）According to the anatomic classification of the siphon, the ICA shapecould be classified into4types: the “U” shape accounting for53%(148/280) and the“V” shape accounting for30%(84/280) are mostly common; and the “C”、“S” shapesare rare and only accounting for17%(48/280)together. Diameter of blood vessel: 4.29±0.63mm in the normal group, and4.90±4.44mm in the sclerosis group,t=1.610，P>0.05. There is no difference in Siphon department blood vessels betweenthe2groups.Break angle of C4、C5: C4value87.23±36.66in the normal group, and87.23±36.66in the sclerosis group.T inspection of2groups,the result is:break angleof C4is t=0.575，P>0.05；C5t=24.16，P>0.05, no significant differencesin the statistical treatment. diameter t=1.610，P>0.05, no significant differences inthe statistical treatment. Age of patients involved in the2groups: age59.17±10.27inthe normal group and67.39±9.32in the sclerosis group, with the result: age t=9.32，P <0.05, no difference between the two.Calcification distribution of Carotid and Siphon Segment of Internal CarotidArtery: C4excurvature calcification96cases（96/352）,account for72%, and inturncalcification58cases （58/352），account for16%. C5excurvature calcification48cases（48/352）,account for72%, and inturn calcification67cases （67/352），accountfor19%. C6excurvature calcification48cases（48/352）,account for14%, and inturncalcification35cases （35/352），account for10%.(2) Character of the normal lumen hemodynamics of internal carotid: blood flowin the crooked siphon department still in laminar conditions, but after2break angles itwill swirl, and the blood flow slow down in excurvation, but accelerates in theincurvature. excurvation hige and incurvature low in tube shear force. Character ofhemodynamic after arteriosclerosis narrowed: Atherosclerotic Plaque caused theblood vessel narrow, which have secondary effects on flood flow, form turbulentflow and low shear force area in the lower reaches of plaque, the more stenosisthe more turbulent the blood flow is, and Concentric stenosis effects more to thehemodynamics than the Eccentric stenosis.Conclusion The anatomic shapes of carotid and siphon segment of internal carotidartery including4types: the “U”、“V” shapes are mostly common, and the “C”、“S”shapes are rare. Calcification pathological changes occur most often in C4lateralcurved. Atherosclerotic Plaque has close connection with age that the incidence isgetting higher when people get older. Blood flow and the morphology of vessel are closely related: the vascular bending shape would have effects on shear force of vesselwall and cause the blood flow turbulence low induce the formation of theAtherosclerotic Plaque and calcification, especially the eccentric stenosis. The swirlof the blood flow with an effect of Anti Atherosclerosis Actions is important to theclinical research. |
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