Food Intolerance Analysis And Observation Of The Therapeutic Effect Of Intolerance-food Elimination In Ulcerative Colitis Patients

Objective: To investigate the relationship between ulcerative colitis (UC) and foodintolerance.Methods: The serum food intolerance-specific IgG (sIgG) level was detected in43ulcerative colitis patients and45health groups by enzyme-linked immunosorbentassay(ELISA). The UC patients who had sIgG-positivity(n=31) were divided intothe diet control group(n=16) and the non-diet control group(n=15). Patients in thediet control group were treated with routine treatment, with their daily dietseliminating the IgG-positive food. Patients in the non-diet control group were treatedwith routine treatment, without diet restriction. After two months of follow-up, theefficacy in the diet control group and the non-diet control group was observed andcompared.Result: The food intolerance-positive rate in43UC patients was72.09%(31/43),while in the45health controls was13.33%(6/45). There was a great statisticalsignificance between the two groups(P<0.01). The total response rate in the dietcontrol group was75.0%during two months of follow-up, while that in the non-dietcontrol group was46.67%, and there was a significant difference between the twogroups (P<0.05).Conclusion: Eliminating the IgG-positive food from UC patients’ diet would behelpful to improve the therapeutic efficacy. High level of serum foodintolerance-specific IgG may be relative to incidence of UC.