Synthesis Of Heteroaryl Sulfides/selenides And N-arylbenzamide Derivatives

This thesis mainly focuses on:(1) synthesis of heteroaryl sulfides andselenides by the coupling reaction of disulfides or diselenides;(2)synthesis of N-aryl benzamide derivatives via copper-catalyzed couplingreaction of benzylamines with aryl iodides.The main contents include:(1) recent progress in the synthesis ofsulfides/selenides using disulfides/diselenides as the starting materials isdescribed;(2) iodine-promoted iron-catalyzed synthesis of4-thiopyrazolederivatives by the direct sulfenylation of1-arylpyrazoles with disulfides.It is noteworthy that diselenides can undergo the reaction smoothly underthe standard conditions. This present method has the advantages ofsimple operation, mild conditions and high efficiency.(3) metal-freeiodine-mediated electrophilic cyclization of2-alkynylanisoles withdisulfides or disenlenides lead to the synthesis of3-thiobenzo[b]furansand3-selanylbenzo[b]furans, respectively. This novel has the merit of environmental-friendly and highly efficient;(4) recent progress in thesynthesis of N-arylbenzamides was reviewed;(5) copper-catalyzedsynthesis of N-arylbenzamides through the coupling reaction of benzylamines with aryl iodides has been developed. In the presence of coppercatalyst, a range of aryl iodides could smoothly underwent the reactionwith benzyl amines to afford the corresponding product in good yields.