Study On Anaerobic Digestion Treatment Technology Of Streptomycin Bacterial Residue

China has become the largest bulk drug producer and export of antibiotics. In theproduction process of fermentation antibiotics, pharmaceutical factory product largeamounts of bacteria residues, which was listed as the national list of hazardous waste dueto it existed potential environmental risk issues. The treatment and disposal of antibioticbacterial residues should be in accordance with hazard solid waste. And so, it is urgent tofind reasonable and safe methods of treatment and disposal of antibiotic bacterial residuesfor pharmaceutical enterprise.This research mainly focused on streptomycin bacterial residues. Firstly, the effect ofalkaline, thermal, alkaline-thermal pretreatment method on streptomycin bacterial residueswere investigated. And then, the BMP evaluated the biodegradability of pretreatmentstreptomycin bacterial residue and confirmed the optimal pretreatment conditions. Finally,it is determined to find the optimal control parameters on anaerobic digestion of treatedand untreated streptomycin bacterial residues.The pretreatment experiment results indicated SCOD and VSS solubilization of allpretreatments from high to low is alkaline-thermal, alkaline, thermal. The BMPexperiment results confirmed appropriate pretreatment can enhanced the biodegradabilityof bacterial residues. Both pretreatment and BMP experiment ascertained that the optimalpretreatment process is alkaline-thermal and the optimal pretreatment parameter is75℃、0.08gNaOH/gTS and2h pretreatment time. Under the Optimal pretreatment conditions,the concentration of SCOD enhanced from6066mg/L to42674mg/L and the concentrationof VSS reduced from37.56g/L to16.55g/L. The SCOD and VSS solubilization is66.39%and44.56%. The accumulative methane yield after pretreatment is435mLCH₄/gVS_added,which enhanced14%than untreated.The anaerobic digestion experiment results confirmed the biodegradability ofstreptomycin bacterial residues is good and treated superior to untreated. In the optimalprocess parameters for the hydraulic retention time of25d, the volume loading of2.33gVS（L· d）^-1, the VS removal of treated bacterial residue was84.40%, which enhanced8.19%than untreated that is76.21%of VS removal; the biogas yield of treated bacterialresidue was0.348L(gVS_added· d)^-1, which enhanced6%than untreated that is0.329L(gVS_added·d)^-1of biogas yield.Owing to higher protein content of streptomycin bacterial residues, the ammonia concentration is very high in the process of anaerobic digestion. When the volume loadingis3.68gVS（L· d）^-1, the methanogens were inhibited from a threshold ammoniaconcentration of3000mg/L.