| Molecularly imprinted polymers （MIP） are provided with advantages such aspredetermination, specific recognition and practical applicability, and MIPs haveoutstanding characters such as acid-proof alkali, high temperature or pressure, simpleand convenient preparation and good stability, so MIP has been widely used in differentresearch fields including sensors, solid-phase extraction, membrane separation andchromatographic analysis. Molecularly imprinted electrochemical sensors （MIECS） ismaking from MIP as the sensitive material, and it has increasingly attractedconsiderable attention in recent years.In this study, three novel MIECS are prepared in different methods on the base ofbrief overview of the development of the MIT and the application of the MIECS. TheMIECS has been successfully applied to food safety detection. The main contentsinclude the following:①Electro-polymerization is a potential method for preparation of molecularimprinting polymer（MIP） electrochemical sensors. Because this method has suchadvantages as simple process，excellent selectivity and the ability to control thickness ofthe films under different charge quantity. A novel sensor based on electro-polymerizedmolecularly imprinted polymer for benzoyl peroxide （BPO） detection is reported. Basedon electro-polymerization and molecular imprinting technology, the sensor wasprepared by electro-polymerizing o-phenylenediamine （OPD） on the glassy carbonelectrode （GCE） with BPO template. The property of the film was investigated bycyclic voltammetry （CV） in the1mmol/L K3[Fe（CN）6] solution. Electrochemicalbehaviors of BPO were investigated by differential pulse voltammetry （DPV）. Thecurrent response of BPO was linear to a concentration in the range of1.86×10-5to1.23×10-4mol/L （r=0.9922） with the detection limit of1.9×10-6mol/L（S/N=3）. Theresult showed that this sensor exhibited quick response and good selectivity.②Based on the efficient electronic transmission and high adsorption capacity ofthe multi-walled carbon nanotubes （MWNTs）, as well as the high recognition ability ofmolecular imprinted polymer （MIP）, a novel MIP electrochemical sensor was developedfor the detection of tert-butyl hydroquinone （TBHQ）. TBHQ was the template. Thesensitive sensor was prepared by electro-polymerizing OPD on the multi-walled carbonnanotubes modified glassy carbon electrode （MWNTs/GCE）. The results indicated that MIP/MWNTs/GCE toward TBHQ have excellent performance and obvious currentresponse. MWNTs was employed to enhance the electrochemical performance of MIPsensor. Under the selected analytical conditions, the DPV response current was linear tothe concentration of TBHQ in the range from1.0×10-4to5.0×10-7mol/L（r=0.9974）withthe detection limit of1.8×10-7mol/L （S/N=3）.③A new-type sensitive MIP electrochemical sensor for selective detection ofsudan I based on sol-gel technology and molecular imprinting technology is developed.The sol-gel membrance was prepared on the multi-walled carbon nanotubes modifiedglassy carbon electrode （MWNTs/GCE） using chitosan as bulk polymer, sudan I astemplate and TEOS as crosslinking agent. Due to such combination, the sensor hadquick response to sudan I. Compared to analytical characteristics of the sensors withand without MWNTs, the results indicated that the current response was improved whenexisting MWNTs. This sensor has good selectivity and sensitivity, and the peak currentresponse was linear to the concentration of sudan I in the range from2.0×10-5to1.0×10-7mol/L, and the detection limit was2.5×10-8mol/L. |
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