Study On Nutritional Status Of AIDS Patients Under Highly Active Anti-Retroviral Therapy In NanChang City

Objective: This study aims to a comprehensive understanding of the nutritionalstatus of AIDS patients under highly active antiretroviral therapy through the dietarysituation investigation, chemistry detection of urine samples and blood parameters,to get the object of study of dietary structure, the nutritional status of water-solublevitamin and blood test results. Nutritional guidance and adjustment measures will begiven according to the results, and preliminary discuss the influence of highly activeantiretroviral therapy to the blood parameters of AIDS patients, provide a valuablereference for nutrition support therapy.Methods: Respondents are90AIDS under highly active antiretroviral therapymore than2years between June1to July1,2009and December5,2010to January5,2011in Nanchang Ninth Hospital,3-day24-hour dietary recall questionnaire andfood frequency questionnaire were used to investigate the dietary intake andnutritional status;20ml of urine collection of respondents was used to measure thecontent of vitamin B1, vitamin B2, vitamin C and creatinine in the urine; Collectedblood samples of respondents,analyse the changing of immunological parameters,virological indicators, liver function parameters and Anemia indicators.Result: The total energy intake of respondents was insufficient, The overallnutrient level was lower than the average of the2002national survey.70%ofpatients had normal BMI. The man-days per standard energy intake of respondentswas1870kcal (7824KJ), and the intake of protein, fat, carbohydrate was57.8g,52.4g,300.6g, respectively. The rate of vitamin B1, vitamin B2and vitamin Ccontent for the normal patients were74.4%,81.1%,72.2%, respectively. After a yearof antiviral therapy, the CD4+T-lymphocytedifferent of respondents increased, andthe viral load decreased. Compared with2009, The liver function index ofrespondents was lower. The difference had statistically significance (P<0.05). Thedifference of anemia index between2009and2010had statistically significance(P<0.05). Conclusion: AIDS patients in this study were lack of food intake, their dietarystructure was irrational and had irregular diet. Highly active antiretroviral therapyhad effectively inhibited the viral growth, but the patient's liver function, anemiaindicators were impacted at the same time. As a result, propaganda and education ofnutrition were necessary between the highly active antiretroviral therapy. As far aspossible according to each patient's condition and nutritional status, developpersonalized treatment options and diet.