Finite Difference Computer Simulation Model Of Intracranial Arterial Blood Pressure Study

Cranial vascular disease because of its common and multiple in clinical, has become a serious threat to people's health and life. And cranial vascular disease becomes one of the important problems of social concern as its high morbidity, high disability rate and high death rate. Intracranial hypertension is a premonition for many cerebrovascular diseases get to worse or generate a cerebral hernia which even can lead to death. So. it is very significant to monitor intracranial pressure efficiently and non-invasively for the diagnosis and treatment of the cerebrovascular disease. Because the intracranial pressure function model can reflect the specific physiological characteristics, in this article, a function model of intracranial arterial blood pressure has been simulated by computer. According to the shortcomings of function model which is too complex, and too difficult in calculation, this thesis proposes a non-invasively simplified one-dimensional finite difference intracranial artery blood pressure model.In this thesis, the finite difference intracranial arteries computer simulation model has been simplified by applying the blood dynamics theory. From the blood dynamic formulas, the basic equations and control equations of the model have been derived out. The characteristic equations from the basic equation are the calculation basis in the cerebral continuous arterial pipes. In these equations, the differential elements have been replaced by the finite elements. At the same times, the linear interpolation method has been used for calculating blood pressure and velocity in the cerebral continuous arterial pipes with the conditions of the boundary and bifurcations. In the branch area of cerebral arterial pipes, control equations are used for the blood pressure and velocity calculations.In order to verify the validity of the model, computer model has been simulated and bring out a series of simulation results in this thesis. From the results, the simulation results (blood flow rate, blood velocity and blood pressure) in the three key pipeline sections (intracranial carotid artery, superficial temporal artery, middle cerebral artery) have been picked out to compared and analyzed. Then, the data from the model simulate results in this thesis have been compared with the data form the model and the clinical data in the literature has been published ever. The results shows that data range of the blood flow and pressure from the simulation model are generally agree with the data from the references, and they have the same change trend. Because the model in the thesis has been simplified, the data of the blood flow and pressure simulation result from the model have lost a part of detail information. The results of the finite difference intracranial blood pressure computer simulation model in the thesis conform to the real human physiological signs. In a word, the model is simplified and it can calculate quickly, and has practical value for the diagnosis and treatment in clinical of the cerebrovascular disease.