Influence Of Diabetes On Prevalence Of Abnormal Microvolt T-Wave Alternans

Background:Subjects with microvolt T-wave alternans (MTWA) in association with structural heart disease have an increased risk for sudden cardiac death. The presence of diabetes (DM) is associated with an increased risk of sudden death, so we tend to study the impact of DM on MTWA prevalence.Methods:We performed a retrospective analysis in198patients referred for routine exercise testing. All patients were divided into4groups:group A (no DM or CHD), group B (DM only), group C (CHD only), group D (DM and CHD). Patients performed a exercise test with assessment of MTWA by the modified moving average method.Results:Logistic regression analysis in all patients showed that abnormal TWA was related to CHD, and prevalent DM. The prevalence of abnormal MTWA was related to HbAlc,but not related to the duration of the DM.Conclusion:Abnormal TWA is a very common condition about24%among people with DM without CHD.