Use Plasma Lactate Levelss And Pumonary Function Before And After Exercise To Evaluate The Exercise Capacity In Patients With COPD

Objectives:This study aimed to use the blood lactate levels as the center to Investigate the role which inspiratory capacity and blood lactate played in the comprehensive evaluation system of patients with moderate to severe COPD, and provide a reference to COPD patients' rehabilitation exercises to ensure the safety, and help these patients choose exercise intensity effectively.Methods:We applicate the Quark PFT-type spirometer from Intermec subjects of Italy for all the patients involved, Test items include normal pulmonary function tests, slow vital capacity, forced vital capacity, maximum minute ventilation, measured:IC (VT+IRV), FEV1, FVC, FFEV1/FVC%. And applicate the AVL blood gas analyzer to test patients' Plasma Lactic acid, PH,PaO2,PaCO2. Applicate the PC-60 refers to the type pulse oximeter in patients before,in and after the process to ensure the safety of the test. All subjects were tested pulmonary function testing, heart rate-. blood gas analysis,blood pressure at the resting state, And measured patients'weight, height, Record transient peripheral oxygen saturation, Fill in the Borg Scale and recorded other contact information. All subjects underwent six minutes walk test, all subjects were measured blood gas analysis, pulmonary function test, heart rate, blood pressure testing immediately after the six minute walk test, and record transient peripheral oxygen saturation, fill in the Borg Scale again.Results:Both the two groups involved in, the 6-minute walk test distance,a drop of arterial oxygen saturation,blood lactate concentration,and inspiratory capacity, the differences were significant. The 6-minute walk distance correlated with the IC, yet there is no significant correlation with FEV1, The blood lactate concentration is negatively related to the walking distance.Conclusions:IC has a better correlation with COPD patients'functional status than FEV1, The blood lactate, as a response to local metabolic factors, reflects the functional status of patients of COPD and their metabolism. And provided a more scientific guidance in functional exercise of COPD patients. If the two indicators are included in the evaluation of COPD,it will be better.