Late Preterm Infants With Respiratory Failure Respiratory Support Efficacy And Outcome Of Observation And Prognostic Analysis

Objective:To observe the efficacy and outcome of respiratory failure in late-pretenn infants treated by respiratory supporting.Methods:Prospective and compared study was done to 58 late-preterm infants who were diagnosed respiratory failure, admitted to our Neonaial imensive Care Uni (NICU) and treated by respiratory supporting between Dec.2009 and Aug.2010, with 55 full term infants as control.Results:In late-preterm infants group, Incidence time of respiratory failure was earlier than the full term infants group(P<0.05). In late-preterm infants group, the primary diseases primarily were pneumonia and respiratory distress syndrome (RDS), which pneumonia, meconium aspiration syndrome (MAS), pneumonia, RDS and pulmonary hemorrhage in the full term infants group. The difference among them was significant(P<0.05). In late-preterm infants group, the recovering of respiratory parameters were slower than the full term infants group after therapy; the ventilator weaning and discharge time were later than the full term infants group; and the rescueing success rate was lower than the full term infants group; The differences among them were significant(P<0.05). In late-preterm infants group, the morbidity of ventilator associated complications and neurological unusual behavior were larger than the full term infants group (P<0.05)Conclusion:The mature degree of late-preterm infants is poor than full term infants. The efficacy and outcome of respiratory supporting can't reach the same level with full term infants. Objective:To screen correlative factors of respiratory failure in late-preterm infants treated by respiratory supporting.Methods:Collect correlative parameters of 58 late-preterm infants who were diagnosed respiratory failure, admitted to our Neonatal Intensive Care Unit (NICU) and treated by respiratory supporting between Dec.2009 and Aug.2010. Compared them with one-way analysis of variance,χ2 inspection and Logistic multiple regression, to screen correlative factors of respiratory failure in late-preterm infants treated by respiratory supporting.Results:By one-way analysis of variance, prenatal use of corticosteroids, sicken duration before respiratory supporting, the value of pH and PaO2/FiO2 of arterial, combined with multiple organ failure, NCIS, respiratory distress score, and orotracheal intubation mechanical ventilation have influence on prognosis of respiratory failure in late-preterm infants treated by respiratory supporting. By Logistic multiple regression, NCIS and respiratory distress score can be independent factors of judging the prognosis of respiratory supporting treatment. The late-preterm infant with respiratory failure may own a bad prognosis. Their sensitiity and specificity respectively are 52.9%,90.2% and 94.1%,55.7%.Conclusion:NCIS and respiratory distress score are independent factors of judging the prognosis of respiratory supporting treatment, and have important clinical value.