Thyroid Ultrasound Differential Diagnosis Of Benign And Malignant Nodules

Purpose:Through the multivariate linear regression analysis, this paper discusses the method of thyroid high frequency ultrasound diagnosis of thyroid cancer, and the clinical significance of ultrasonic characteristics are analyzed and discussed the importance of ultrasonic characteristics of thyroid benign and malignant nodules diagnosis.Methods:Retrospective 295 cases of thyroid disease patients (not including a second surgery and diffuse toxic goiter, Graves disease, GD) of xiwu ward from January 2010 to January 2011. The pathological diagnosis of patients (the dependent variable)with the boundary, calcification (described:without calcification, coarse calcification, micro calcified), structure and echo four sonographic features, Applying SPSS software, a forward multiple linear regression analysis, this paper discusses the influence of thyroid cancer. According to the common international standards:the largest diameter> 2mm calcification is called coarse calcification, the largest diameter< 2mm calcification is called microcalcification. coarse calcified including massive calcification, patchy calcified and peripheral calcification.Results:In 295 patients, benign patients is 219, patients with thyroid cancer is 76 cases. Calcification 160 cases,while coarse Calcification 55 cases(34.38%), including begign 46 cases and malignant 9 cases;fine Calcification 105 cases(65.63%),including begign nodules 46 cases and malignant 59 cases; boundary unclear cases is 83(28.14%) including begign nodules 46 cases and malignant 37 cases; Solid nodules is 241 cases (81.69%) including begign nodules 169 cases and malignant 72 cases; Hypoechoic nodule 65 cases (22.03%) including nodules 31 cases and malignant 34 cases. All four common sonographic features,the boundary,calcification and echo of the nodules opt-in equation after the regression analysis,the nature of capsule or solid is not significant,and in the process of analysis, coarse Calcification is dropped because of P>0.05.As boundary(coefficient 1.056),echo(coefficient 1.263),fine calcification (coefficient 2.759),considering of the coefficient,we infer that fine calcification has the biggest influence in diagnosis of thyroid benign and malignant.Conclusions:1) Thyroid ultrasound play an important role in the diagnosis of thyroid benign and malignant nodules, providing important information for the clinical treatment.2) boundary unclear, hypoechoic nodules, macro calcification are important signs for the diagnosis of thyroid cancer in ultrasound images. And macro calcification is particularly important.3) The coarse calcification and nodule composition does not statistically significant in the study of thyroid cancer diagnosis, that need further diagnosis according to the clinical manifestation.