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The MR Susceptibility Weighted Imaging In The Application Of Glioma

Posted on:2012-03-27Degree:MasterType:Thesis
Country:ChinaCandidate:B H ZhangFull Text:PDF
GTID:2214330338469647Subject:Medical Imaging and Nuclear Medicine
Abstract/Summary:PDF Full Text Request
Objective:Comparative analysis of glioma in MR susceptibility-weighted imaging(SWI) for clinical diagnostic imaging performance characteristics。To investigate the feasibility of SWI in grading of glioma..Methods:36 cases of glioma identity by pathological diagnosis, using Siemens 3.0T MR routine sequence scanning (including T1WI, T2WI, T2-FLAIR and T1 enhancement) and SWI sequence scanning, image of high qualification by two doctors do not know under the conditions of tumor grade to grade analysis and by calculating the percentage of conventional statistical analysis and comparison of sequences (T1 enhancement), SWI sequence consistent with the rate of pathological grade. Based on retrospective analysis of pathological grade of glioma tumor hemorrhage SWI sequence size, the number of tumor blood vessels using F test and ANOVA analysis of the data.Results:Glioma in conventional MR T1WI showed homogeneous low signal in 24 cases (66,67%) were mixed signal 12 cases (33.33%); T2WI showed homogeneous high signal in 20 cases (55.56%), were mixed signals in 16 cases (44.44%); clear boundary of tumor in 15 cases (41.67%); boundaries less clear in 21 cases (58.33%). Enhanced CT showed no enhancement in 5 patients (14.89%), annular in 10 patients (27.78%), sheet 8 cases (22.22%), irregular shape enhanced 13 cases (35.11%); SWI showed the tumor than the surrounding tissue signal slightly lower, in the min IP-SWI calculate the number of bleeding and vascular tumor size, the phase diagram shows calcification, including 24 cases showing calcification (66.67%). SWI and T1-enhanced scan and the pathological grade of the match rate was 75%and 55.56%, SWI preoperative grading consistent with the higher rate of pathology. In SWI, pathological grade gliomas of different bleeding volume, the overall objectives of small blood vessels within the tumor and the tumor is proportional to the degree of malignancy, and all levels of gliomas within the micro-bleeding volume levels the number of small blood vessels within the tumor were significantly different.Conclusion:The image of SWI sequences in glioma have a certain character, SWI can be used as complementary to conventional MR sequences in the diagnosis of glioma, and for the preoperative grading of gliomas.
Keywords/Search Tags:glioma, pathological grade, susceptibility-weighted imaging(SWI), MRI
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