The Phenotype And Lifespan Of Caffeine On C.Elegans

Caffeine is a popular composition in the world and it can affect the mind or mental process. Different kinds of teas contain caffeine, and that's why we can not sleep after drinking tea. As people know that there is much caffeine in pu'er tea, but pu'er tea doesn't affect our sleep. So this paper studies whether the caffeine combined with the polysaccharide and the concentration of inhibitors in pu'er tea, proved most of the caffeine is free existence and the content of inhibitor is very low in pu'er tea, indicating that there is other factors can inhibit the effects of caffeine. Thousands of research about caffeine has been done. But the effects of caffeine on Caenorhabditis elegans have never been reported. This article use C.elegans to research the effect of caffeine. It's important that is we found caffeine can prolong the lifespan of C.elegans. Compairing with the idea of caffeine is harmful to person's health, this result was against the old idea, and also we research the mechanisms with several mutated C.elegans, such as DR1568,TJ1052,CF1038å'ŒVC199,eventually, We found it is related with the pathway of IGF-1.