Effects Of Organic Mn On Growth Performance, Immunity And Anti-Oxidation Activity In Normal And Coccidia-Infected Broilers

The present study probes into the effects of supplementing oxy-methionine at different levels to daily diets on normal and coccidia-infected broilers'growth performance, immunity and anti-oxidation activity in two experiments.The purpose of Experiment 1 is to investigate the effects of methionine hydroxy chelated Mn at different levels (Mintrex Mn) on broilers'growth performance, immunity and anti-oxidation activity. A total of 270 one-day male Arbor Acres broilers were randomly allotted to 5 treatments with 9 replicates (cages) of 6 chicks each and fed with corn-soybean basal diet (negative control), sulfate Mn diet at 60 mg/kg (positive control) and organic Mn diet at 30, 60, and 90 mg/kg (experimenting groups) respectively. The entire experiment was divided into two stages (early and late stages). The results showed that broilers'feed utilization ratio, immunity and anti-oxidation activity inceased as they were fed with basal diet supplemented with organic Mn. Feed utilization ratio, Tibia Mn deposition, phagocytic index of macrophages and Mn-SOD enzyme activity in livers increased linearly as dietary organic Mn increased. There was a quadratic curve relation between organic Mn level and anti-NDV. The application of organic Mn to daily diets at 30mg/kg can be substitute for inorganic Mn and functions better than the latter in improving broilers'growth performance. With respect to immunity and anti-oxidation activity improvement, the supplementation of organic Mn at 60 and 90mg/kg performs better than inorganic sulfate Mn.Experiment 2 was conducted to evaluate the effects of supplementing Mintrex Mn at different levels to dialy diets on coccidia-infected broilers'growth performance, immune responses and anti-oxidation activity. A total of 540 one-day male Arbor Acres broilers were randomly assigned to 5 treatments before 0-21days and fed with corn-soybean basal diet, sulfate Mn diet at 60 mg/kg and organic Mn diet at 30, 60, and 90 mg/kg (experimenting groups) respectively. At 21 days of age, half of each treatment was administered with 2.0×104 sporulated E. tenella oocysts and 5.0×104 sprulated E. acervulina oocysts into the crop via an oral gavage. Uninfected groups were injected with equivalent saline water. The results are as follows: infected coccidia significantly reduced the broilers'growth performance, immunity and anti-oxidation activity. The supplementation of Mintrex Mn to dialy diets can alleviate the impairment caused by coccidia in broiler organisms. Compared with the group supplemented with sulfate Mn, the Mintrex Mn supplementation at 60 and 90 mg/kg is more effective than sulfate Mn in reducing oocyst shedding, and the supplementation at 30mg/kg had higher DWG and FI. There was a significantly interactive effect on DWG and tibia Mn deposition between organic Mn level and coccidian infection.