Microreactor 1,2,4 - Triazine Compound Synthesis And A Polyacrylic Derivative Surface Active Agent, Synthetic Studies

Chapter 1:Micro-flow reactor is a new type of continuous flow reactor with effi cient heat and mass transfer. When running organic chemistry reaction in microrea ctor, reaction temperature, reaction time and ratio of reactants can not only be acc urately controlled, re-optimization in production process at each stage of scale-up can also be avoided. Therefore, the using of microreactor to optimize various orga nic reactions will become a new prospect of organic synthesis research field. The papers detailedly introduced the structure characteristics, the properties such as hea t and mass transfer, continuous flow of microreactor and application and developm ent of microreactor; And the development and application of organic synthesis in microreactor was reviewed. We introduced the strategies and methods of designing and constructing microreactor system we built, and expounded the features and a dvantages of the microreactor. By using a back pressure vavle in the end of our microreactor, the reaction system obtained continuous flow pressure environment w hich promoted successfully the synthesis of 2,4,5-trisubstituted-1,2,4-triazine deriva tives. This method was applicative and different kinds of various hydrazides and d iketones were perfectly applied. Under the condition of high temperature (180℃) that was above the acetic acid solvent boiling point and just short residence time (5min), the yield of 2,4,5-trisubstituted-1,2,4-triazines were 70%-85% which w as higher than the reaction performed in traditional reactor. In camparison to micr owave reactors, scaling up for the continuous flow microreactor system can be eas ily achieved (numbering up).Chapter 2:Polyacrylic acid derivatives was a kind of water-soluble high molecular surfactant which can be used widely for food, feed, textile, papermaking, water treatment in industrial field, also can be used for health supplies, forestry and gardening, civil construction, etc. In civil construction industry, polyacrylic acid derivatives is a kind of new and efficient water reducing agent, and the most common and important concrete admixtures. Low molecular weight polyacrylic acid is a new, recognized green water reducing agent in home and abroad with high decrease water rate, keeping good scattered performance, small slump loss, wide cement adaptability etc. Due to these advantages of Polyacrylic acid derivatives efficient water reducing agent, the research of Polyacrylic acid derivatives become a worldwide hotspot. As the development of Polyacrylic acid derivatives water reducing agent research, amides Polyacrylic acid water reducing agent has become a new subject in this field. In camparison to the traditional Polyacrylic acid derivatives water reducing agent, different functional groups such as amino, imino, amides groups, etc, were introduced into nonionic side chain of amides water-reducing agent molecules, these groups can form strong hydrogen bond with water molecules or themselves by the interaction with each other. The strong adsorption ability of amide groups, and the introduction of amide groups can also improve the adsorption ability of water reducing agent. The research of the methods of this kind of water reducing agent was significant. The paper introduced the current research situation, work mechanism and research significance of polycarboxylic acid water reducing agent, etc. We explored the synthesis methods of amides polyacrylic acid, analysed and detected the structure and performance of products.