The Preparation, Characterization And Potential Applications Of The Carbonate/Organnic Hybrid Materials With Composite Pores Structure

Porous material has been developed rapidly in modern material science as a kind of multifunctionalmaterial, especially the ones the pore size of which is around nanometer. Because of the particular porousstructure, the materials are of many special characteristics and applied widely, which arouses greatattentions in the field of science as well as industrial and commercial circles. Its applications involvechemical, pharmaceutical, environmental protection and so on. With the development of porous materials,composite-pore material emerges as a new style different from those porous materials with single pore size.It has two or more than two kinds of pore sizes and different sized pores are arranged regularly, so itpossesses more wonderful functions and would be applied more widely. In addition, on the basic ofcomposite-pore material, organic/inorganic hybrid materials with composite-pores have special constituentand also have attracted much attention because of the specific physical and chemical properties.In this article, we simply synthesized carbonate/polysaccharose hybrid porous materials with specialmorphologies successfully through a facil and nontoxic method and studied its potential applications indrug loading and transportation as well as the waste water treatment. First of all, we introduced theclassification, characteristics and applications of porous materials and then discussed more about theconcept, features as well as applications of composite-pore material. Finally, the research content andcontext and features of this dissertation were also presented.In the selection of this article, we chose polysaccharide extracted from edible fungi with extensivepharmacological activities as organic matrix and lentinan was mainly tried. Calciumcarbonate/polysaccharide hybrid porous microsphere was synthesized through a facile method in a shorttime and its capability in drug load and transportation and waste water treatment was studied. Furthermore,barium carbonate/soluble starch was prepared in room temperature using soluble starch as matrix. Theeffect of several factors such as the amount and concentration of raw material and reaction time werestudied systematically. Samples was characterized by scanning electron microscopy(SEM), field emissionscanning microscopy (FESEM), X-ray powder diffraction (XRD), transmission electron microscope (TEM),Thermogravmetric/Differential Thermal Analyzer (TG-DTA), Fourier Transform Infrared Spectrometer (FT-IR), High resolution transmission electron microscope (HRTEM), morphology, size and components ofhybrid porous complexes were tested. Furthermore, Ultraviolet-Visible Spectrometer (UV-VIS) and atomicabsorption spectrophotometer (AAS) were also applied to analyze the application of calcium carbonate indrug load and transportation and waste water treatment.The results are as follows: calcium carbonate particles we received are complex porous spheres withdiameter of1-2μm.Through drug transportation experiments we discovered that drug released amount ofcarbonate/polysaccharide complex porous materials loaded with Doxorubicin varied with pH value ofsystem. The amount of drug release ascend with reduce of pH value, which demonstrates that complexsystem are sensitive to pH value of surrounding environment. So it would release drugs selectively to theweakly acidic cancer cells and will be a promising material as drug carrier. From the results of adsorptionof heavy metal ion, carbonate/polysaccharide complex porous materials show excellent performance ofadsorption of high concentration or trace metal ion. Morphology of Barium carbonate/starch hybrid porouscomplex varied with concentration of reactants and reaction time, such as spindle shape, peanut shape,spray shape or sphere shape.In this dissertation, using polysaccharide extracted from edible fungi and soluble starch as organicmatrix, carbonate/polysaccharide hybrid porous materials with excellent performance were producedthrough facile method, which will be a guide for the research of synthesis mechanism of hybrid porousmaterials.