Electrospinning Of Thermo-Responsive PNIPAAm/PAMPS Nanofibers And Their Properties

Electrospinning is an effective and normal technology for electrostatic fiber formation. This technology utilizes electrical forces to produce polymer fibers of which diameters ranging from nanometers to micrometers and it has attracted much attention in the past decade. Electrospinning is the only way to produce a great quantity of continuous nanofibers.The thermo-responsive fibers of Poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS) and Poly(N-isopropylacrylamide) (PNIPAAm) were prepared through electrospinning. A new and simple electrospinning method has been successfully developed for the fabrication of well aligned PNIPAAm/PAMPS nanofibers. The PNIPAAm/PAMPS nanofibers film with Nifedipine (NIF) were produced with addition NIF in electrospun solution. Disorder PNIPAAm/PAMPS nanofibers were prepared, and the orthogonal experiments were performed to investigate the best conditions of electrospun, when the solution concentration was 7%, applied voltage was 10 kV, tip-to-collector distance was 20 cm, and injection rate was 0.005μL?mindiameter of PNIPAAm/PAMPS nanofibers was 148.42 nm. The CAs of PNIPAAm/PAMPS nanofibers film were measured in 20℃and 40℃, and the film switched from superhydrophilic to superhydrophobic.Well aligned PAMPS/PNIPAAm nanofibers were prepared by improvement of tradition electrospinning apparatus. The ordered degree of the aligned fibers was increasing with the electrospun time and the aligned PAMPS/PNIPAAm nanofibers'diameter was smaller than the disorder's which prepared in the same conditions. The PNIPAAm/PAMPS nanofibers film with NIF were produced and the diameter of the PNIPAAm/PAMPS nanofibers with NIF was bigger than the fibers without NIF.The PNIPAAm/PAMPS nanofibers film with NIF was still thermo-responsive which switched from superhydrophilic to superhydrophobic when the temperature change from 20℃to 40℃. The morphology of the PNIPAAm/PAMPS nanofibers film with NIF were changed with the temperature in the dropping water experiments which effected the release of NIF.