The Study Of Hemocompatibility Of Fluorinated Diamond-like Carbon Films

The fluorinated diamond-like carbon (F-DLC) films were prepared by reactive magnetron sputtering under different discharge powers,gas flow ratios with trifluoromethane (CHF3 ) and argon (Ar) as source gases and pure graphite as a target on the surface of 316L stainless steel (SU316L).The factors which influence the blood compatibility were discussed by double-stilled water, BCA and FTIR spectra. The results showed that the surface of SU316L coated with F-DLC films could obviously decrease the number of adherent platelets and dramatically reduce the deformation of platelets, accordingly have a higher albumin to fibrinogen adsorption ratio than that of SU316L substrates, which indicated that the SU316L coated with F-DLC films could improve the blood compatibility. The films had the highest ratio of albumin to fibrinogen adsorption and the best hemocompatibility when the ratio of gas flow was 2:1 and the discharge power was 180W. Furthermore, the results of contact angle,surface energy of the films and FTIR spectra showed that the ratios of albumin to fibrinogen adsorption and the hemocompatibility of F-DLC films on the surface of SU316L were correlated with the surface energy (hydrophobic nature) of films and the contents of -CFx bonds (the content ratios of C-F to C=C) in films. The modulation of blood compatibility of the films could be realized by the control of the ratios of source gas flow and the discharge powers.