| Objective: Thromboangiitis obliterans is a serious disease, endangering the quality of human life, belongs to Chinese medicine, "off gangrene" category. More common in men aged 20-40, mainly affects the limbs, especially the lower limbs, the small artery and its accompanying veins and skin veins. TCM treatment of thromboangiitis obliterans in the process has obvious advantages, but modern physicians in the treatment of thromboangiitis obliterans in both breadth and depth are not enough digging. This paper seeks to understand and summarize a whole thromboangiitis obliterans treatment development of the dialectical law of for further research thromboangiitis obliterans basis for improving clinical efficacy of thromboangiitis obliterans, provide a scientific basis.Materials and Methods: Based on the medical information resource system V6.32 VIP in 1989 ---- 2009 published the treatment of thromboangiitis obliterans cases related to data collection, collation, the last entry Epidata unified database, and then SPSS statistical software combines international authority on the symptoms of vasculitis, the use of herbs, etc. frequency statistics, factor analysis, cluster analysis, and frostbite history, smoking history and disease necroses for contingency table analysis and logistic regression classification II analysis of mathematical statistics.Results:1. Through more than 15 times the frequency of symptoms of factor analysis, summarized in seven groups affect the symptoms of vasculitis syndrome type composition; Fl: red tongue Jiang, yellow and greasy moss, pulse a few strings, F2: fatigue weakness, palpitations shortness of breath, emaciation, F3: dry stool, urine short red, F4: fine hair loss, nail thickening, rough skin, muscle atrophy, F5: numbness of extremities, decreased pulse Yang instep.2. By more than 15 times the frequency of the symptoms of cluster analysis to form four more meaningful clustering combination of symptoms, namely C1: thin white tongue fur, pulse fine astringent, skin color pale, pale tongue, limbs Cool, hi, warm cold, intermittent claudication, numbness, instep Yang weak pulse, pain at night drama; C2: short red urine, dry stools, yellow and greasy tongue coating, scarlet tongue color, pulse a few strings, ulcer or necrosis; C3 : Shenpi fatigue, palpitations shortness of breath, body weight loss, eat less poor appetite; C4: affected part ecchymosis, dark tongue color purple, rough skin, fine hair loss, muscle atrophy.3. Through more than 15 times the frequency of drugs factor, cluster analysis, nine were formed more meaningful Drug combinations; and this frequency of these drugs come mainly through the liver, kidney, heart, spleen appeared a total of 42 times, accounting for 67.74%. One warm, heat a total of 11 drugs, 55% of the total, cold, cold of a total of 98 drugs, which account for 45%. Yao Wei to sweet, bitter, Xin-based, accounting for 31.91%, 23.4%, 21.28%.4. Summed up the modern treatment of thromboangiitis obliterans patients in the primary drug of 25 flavors, Traditional medicine the most,up to 166 times, make up the product of blood and 255 times, heat there were 161 drugs.5. Excluded frostbite history factors, smoking history happens vasculitis usually occurs after necrosis in patients with no history of smoking 16.197 times. Exclude smoking history factors, usually with necrosis after frostbite history happens there is no vasculitis patients with a history of 8.263 times the frostbite.6. By two categories of logistic regression analysis, after suffering from vasculitis necrosis probability forecasting model is: Logit P =- 1.837 +2.785×smoking +2.112×frostbite7. For no necrosis of the forecasting accuracy rate of 64.7%, while the forecast for the accuracy of necrosis up to 85.1%, the total prediction accuracy was 78.2%.Conclusions:1. Thromboangiitis obliterans syndrome has four basic alpine obstruction syndrome, blood stasis type, Fujian College, Qi and Yin Deficiency type, cluster obtained evidence and clinical evidence derived from basically the same type shows that the clustering of the syndrome have a certain scientific, practical and credible.2. Summary of the modern treatment of thromboangiitis obliterans cases in the main drugs, these drugs can best embody the thromboangiitis obliterans syndrome classification group ownership, and treatment. Ferrite blood shortage prompted the wind cold dampness evil violation of the human body, the body of Fujian College should be a total of thromboangiitis obliterans syndrome type ownership group, and Blockage of blood contact in patients with thromboangiitis obliterans is an important pathogenesis, display dispelling evil, righting, blood is the treatment of thromboangiitis obliterans Chinese general knowledge.3. Frostbite history and smoking history are risk factors for necrotizing vasculitis occurred, ruled out the history of frostbite factors, smoking history happens vasculitis usually occurs after necrosis in patients with no history of smoking 16.197 times. Exclude smoking history factors, usually with necrosis after frostbite history happens there is no vasculitis patients with a history of 8.263 times the frostbite. |
