Rheumatoid Arthritis-chip Technology And Quality Standard

An allergic disease, arthritis, is a major manifestation of rheumatic fever, often accompanied by acute fever and joint pain. Humanity has not yet fully understood causes of the disease. According to symptoms, epidemiological and immunological analysis of Statistics, human hemolytic streptococcal infection is closely related to arthritis. Currently noted that infection is also related to this disease .Modern medicine has mainly taken the disease with Penicillin control of streptococcal infection, Antipyretic and anti-inflammatory salicylic acid preparations to improve the symptoms of pain. Accompanied by myocarditis patients consider the use of adrenal cortex hormones. However, these treatment methods, it is difficult to achieve the effect of healing, these methods are not fundamentally in the treatment of the disease. Of TCM in the treatment of arthritis there is a unique edge, a vast reservoir of potential.Arthritis is a traditional Chinese medicine, "arthralgia-synadrome" Category. Traditional treatment methods of the disease is to supplement the gas and blood, in addition to rheumatism, blood circulation.Arthritis tablets are used to treat arthritis, rheumatism.It is a tablet dosage form by prescription through the changing. The drug is characterized by good efficacy and few side effects. This article aims to establish an effective and reasonable for the drug quality standards, with a view to better control the quality of the drug.Arthritis tablets are a drug, which can increase blood circulation. Arthritis tablets are used to remove rheumatism, treatment of Waist-Leg pain, rheumatoid arthritis, etc. It is composed of 17 Chinese herbal medicines. Therefore, it is a very complex process to ensure that all active ingredients are not destroyed and totally used as medicine. Therefore, we have to study their craftsmanship. However, the preparation also contains toxic ingredients. Therefore, we should also fully establish its quality control methods. We use the thin-layer chromatography for Qualitative identification of Chinese herbal medicines.We use HPLC to measure the content of toxic ingredients and active ingredient. Finally, we establish a rational and effective extraction, preparation process and a complete set of reasonable standards.Identification of the use of HPLC/ESI/MS2 RA film chemical composition of the 11 alkaloids, L-ephedrine,L-N-methyl-ephedrine,pseudostrychnine,Strychnine,Brucine, isostrychnine,icajidine,pseudobrucine,strychnine N-oxide,Vomicine,15-Hydroxyicajine。Which, in addition to strychnine and ephedrine hydrochloride, Rheumatoid arthritis from other alkaloids are found in the film for the first time。Qualitative analysis of the use of HPLC/DAD/MS2 with high accuracy, high sensitivity, To further clarify the experimental work described in rheumatoid arthritis tablets chemical constituents of alkaloids and the establishment of quality control of the foundation。...