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Non-diabetic Cardiovascular And Cerebrovascular Accident And Emergency And Acute Phase Blood Glucose Levels

Posted on:2011-05-21Degree:MasterType:Thesis
Country:ChinaCandidate:L ChuFull Text:PDF
GTID:2204360305978905Subject:Department of Cardiology
Abstract/Summary:PDF Full Text Request
Cardio-cerebral vascular diseases causing the death of major diseases are a serious threat to human health. Acute coronary syndrome (ACS) is the type of a poor prognosis in coronary heart disease, including those with unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI). ACS is due to instability of plaque rupture and erosion complicated by thrombosis, vascular spasm and microvascular thrombosis under the action of multiple factors such as caused by acute or subacute myocardial oxygen reduction. Compared with Western industrialized countries, China's cerebrovascular disease morbidity and mortality rates are higher than cardiovascular disease. Cerebrovascular disease in the elderly has become harmful to China's health and lives of major diseases. Cerebral infarction accounting for about 60%to 80%in stroke; morbidity, mortality and disability are also high. Cardio-cerebral vascular accident and emergency are often accompanied by hyperglycemia, although this phenomenon has been part of the report, but the current acute stage of the clinical importance of hyperglycemia is not high, mainly due to the limitations of past research. This study was to investigate the acute coronary syndrome and acute cerebral infarction and acute phase of the relationship between blood glucose levels, to provide guidance for clinical practice.Association between the blood glucose level and acute coronary syndrome with non-diabetic patientsObjective:To observe the relationship between the blood glucose level and acute coronary syndrome with non-diabetic patients. Method:Blood glucose level were monitored at the admission in the total of 198 cases of ACS received angiography with non-diabetic patients. According to the blood glucose level, all patients were divided into the first group (normal blood glucose level), the second group (blood glucose level in the 6.1-7.8mmol/L) and the third group (blood glucose level higher than 7.8mmol/L). Comparing the clinical characteristics of each group and coronary artery lesions (Gensini score) and cardiovascular complications and mortality. Results:the third group of Gensini score, serious arrhythmia, heart failure, cardiogenic shock and mortality was significantly higher than the second group and the first group. Similarly, the second group of Gensini score and cardiovascular events was significantly higher than the first group. Conclusion:The blood glucose level during hospitalization in non-diabetic patients with acute coronary syndrome was positively correlated with the degree of coronary artery disease and cardiovascular events.Association between acute hyperglycemia and clinical in non-diabetic patients with acute ischemic strokeObjective:To observe the relationship between acute hyperglycemia and clinical in non-diabetic patients with acute ischemic stroke. Method:The values of fasting plasma glucose(FPG) in 48h were monitored in the total of 77 cases of acute cerebral infarction by MRI or CT examination confirmed in non-diabetic patients excluding lacunar infarction. According to FPG, all patients were divided into hyperglycemia group (FPG≥6.1mmol/L) and normal glucose group (FPG<6.1 mmol/L). Results:The blood glucose has nothing with the infarct location, but has association with the infarct size. Compared with normal glucose group, hyperglycemia group in nerve function deficit has more aggravation and higher mortality. Conclusion:acute hyperglycemia can predict the prognosis in non-diabetic patients with acute ischemic stroke, so should has been caused enough attention.Non-diabetic cardio-cerebral vascular accident and emergency, the acute phase blood glucose level can reflect the severity of the disease. Acute coronary syndrome with acute blood glucose level increased, more severe degree of coronary artery disease, Gensini score higher; patients with severe arrhythmia, heart failure, cardiogenic shock, the incidence and mortality increase. Acute blood glucose level in patients with acute cerebral infarction and cerebral infarction site has nothing to do with the blood glucose level increased, infarct size larger; neurological deficit increased the occurrence of deterioration and death. Cardio-cerebral vascular accident and emergency during the acute stage of high blood sugar should be actively processing can improve the occurrence of cardiovascular events and cerebral infarction in patients with functional recovery.
Keywords/Search Tags:Acute coronary syndrome, ischemic stroke, hyperglycemia, cardiovascular events, nerve function deficit
PDF Full Text Request
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