Plasma C-reactive Protein And Lipids Differentially Expressed Clinical Significance

Purpose: Research on patients with coronary heart disease C-reactive protein and serum lipids differentially expressed, find may be related to asymptomatic coronary heart disease associated with type-specific markers of clinical assessment. And Chinese medicine Shuxuening Injection influence CRP and lipids.Method: From 2006 to 2008, from our hospital out-patient physical examination of people screened 54 cases of occult coronary artery disease patients and 54 healthy people , The enzyme-linked immunosorbent assay (ELISA) detected 54 cases of healthy people and 54 cases of patients with coronary heart disease and CRP ,TC, TG, HDL-C, LDL-C, apoB , apoA level in serum;Meanwhile, patients with coronary heart disease are divided into Plus TCM treatment group (26cases) and conventional treatment group (28cases), Detect again lipids, serum CRP concentration after 15 days.Results:coronary heart disease serum CRP, TC, TG and LDL-C was significantly higher than the control group, the difference was statistically significant (P <0. 05), and also CRP and TC, TG, LDL-C was positively correlated with each other, coronary heart disease serum HDL-C levels were significantly lower than the control group, the difference was significant (P <0. 05), and CRP and HDL-C was a negative correlation; Add medicine Shuxuening Injection serum CRP and TC, TG, LDL-C content than the conventional therapy group decreased significantly (P <0. 05), Serum HDL-C content increased, compared with conventional treatment group, there is significant difference (P <0.05).Conclusion:CRP is an independent cardiovascular disease risk factors, occult coronary heart disease in patients with CRP and lipid metabolic disorders is related; Of silent myocardial ischemia in patients with CRP early detection of coronary heart disease prevention and treatment are important; Shuxuening Injection in patients with coronary heart disease can effectively reduce serum CRP and TC, TG, LDL-C, apoB levels, increased HDL-C, apoA is conducive to preventing atherosclerosis further development.