Tune Bile Mixture B Rabbit Cholecystectomy Postoperative Bile Secretion And Composition Of The Experiment

Purpose: Adjusts gallbladder mixture B through the observation after thedomestic rabbit gallbladder excision method the bile secretion's influence, studies its advantage gallbladder function to form to biliary duct's machinery flushing, dilutes the partial inflammation medium density, after promoting the gallbladder excision method, biliary system function restoration.Material and method: Takes domestic rabbit 24, female and male does notarrest, about body weight 2. 5kg, fasts to be unable to restrain water 12h, the epigastrium technique area prepares the skin, after the weighing, divides into 3 groups stochastically, namely the blank group, the aseptic distilled water control group and adjusts the gallbladder mixture B group of 3 monitoring teams. The domestic rabbit (30mg/kg) anaesthetizes with 3% pentobarbitol sodium, lies supine the rabbit fixes on the rabbit board surgery table, the epigastrium technique area convention disinfection, is accepted after passing an examination center the abdomen the margin, the cascade cuts open the abdomen, the hematischesis truly, exposes the stomach, the duodenum, the gallbladder and the choledoch, after tying up the ductus cysticus, excises the gallbladder, then the vertical line cuts open the choledoch (long margin approximately 0.5cm), in the choledoch, lays aside a drainage tube to its near-end, the drainage tube uses in the bile drainage, under the drainage tube meets a drainage bag, for the correct measurement domestic rabbit bile current capacity, the choledoch margin far-end ligation, Before Guanfu after the domestic rabbit oral cavity under the stomach tube to the duodenum, looks up the non-activity hemorrhage and The bile, the cascade turns off the abdomen, the technique finishes. After treating the domestic rabbit regains consciousness, after the stomach tube separately pours into the aseptic distilled water and adjusts gallbladder mixture B each 15ml, simultaneously and starts to time, Every 6 hours measure one time and simultaneously once more use the above measurement and the method give the medicine, altogether 4 times. Observes and records the blank group, the aseptic distilled water control group and adjusts the gallbladder mixture B group, 3 group of domestic rabbit bile current capacity and bile ingredient change situation.Results:1. The domestic rabbit gallbladder excision method model success preparation, fills medicine easier control experiment's advance through the stomach tube duodenum.2. Adjusts the gallbladder mixture B group to compare the control group bile secretion obviously to increase, P<0.01.3. Adjusts the gallbladder mixture B group to compare the control group bilirubinthe content to change not obviously, P>0.05.4. Adjusts the gallbladder mixture B group to compare in the control group bile the bile acid, the cholesterol and the phospho-lipin average density change not remarkable difference, Compares P>0. 05 with the distilled water group, compares P>0. 05 with the control group.Conclusion:1. After adjusting gallbladder mixture B can promote the domestic rabbit gallbladder excision method, bile secretion.2. Adjusts gallbladder mixture B does not have the influence to the domestic rabbit bile essential component and the density.