Forefront Of Cool Piece, And Indications Of The Main Pharmacodynamic Pilot Study

Objective: This subject ,which belongs to the exploitative program of traditional Chinese medicine, is a experiment of pharmacodynamics mainly about the function and specific remedy of QIANLIE DESHUANG tablet (a tablet which is good for prostate), a kind of chinese medicine compound preparation whose function is to cure chronic prostatitis and proliferation of prostate gland. This experiment observes the main pharmacologic effects and the reaction to pain caused by chemical and physical factors after being used the QIANLIE DESHUANG tablet through the duplication of prostatitis and proliferation of prostate gland model.Method: To observe the suppression of proliferation of prostate gland induced by Propionate Testosterone after being used the QIANLIE DESHUANG tablet through the duplication of prostatitis and proliferation of prostate gland model and to investigate the pharmacologic effects of the preparation of curing the prostate diseases through the condition of suppression of acute prostatitis caused by E.coli, the condition of suppression of granulation proliferation in the acute exudative inflammation caused by Carrageenan Levin Plastic and in the chronic proliferative inflammation caused by Cotton Subcutaneous Implantation, and the condition of mitigation of pain caused by chemical and physical factors.Results: 1. The observation of the experiment to suppress proliferation of prostate gland by using QIANLIE DESHUANG tablet illustrates: QIANLIE DESHUANG tablet (1.8 g·kg-1)by oral administration can decrease the wet weight index of prostate gland in the animal model of prostate proliferation of the castrated rats induced by Propionate Testosterone ,and has the suppression effects to rats'prostate proliferation induced by Propionate Testosterone, which prompts that this preparation has an improvement effect to prostate proliferation model.2.The research of the anti-inflammatory effects of QIANLIE DESHUANG tablet illustrates that it has an effect of suppression to acute prostatitis caused by E.coli, to granulation proliferation in the acute exudative inflammation caused by Carrageenan Levin Plastic and to chronic proliferative inflammation caused by Cotton Subcutaneous Implantation. 3. The experiment of analgesic effect of QIANLIE DESHUANG tablet illustrates: QIANLIE DESHUANG tablet has weak effect to pain caused by chemical factors (acetic acid process) and physical factors (hot plate apparatus) .