Systematic Reviews Of The Domestic Chinese Medicine Treatment Of Female Climacteric Syndrome

The Background: The climacteric syndrome is a common and polidisease in the gynecology. Most of the foreign medical adopt the hormone replacement therapeusis, but long-term taking medicine can result to increase the incidence rate of the cancer of the membrane in the uterus, and the breast. In the ancient and modern literature, it has been regarded and reported that the Chinese traditional medicine treats can lead this kind of sickness to be effective. At present oneself has many the stochastic comparison clinical test research which drafts about the menopause synthesis, but its result has dispute. So the systematic evaluation of these treatments is very important. Now the clinical investigation does not think highly of the methodology that affects the extence of the investigative conclusion and the admittance of the western medical. The method and result of the Evidence Based Medicine and systematic analysis has been admitted and thought highly of by the international-medicine and the medical-decision department day by day. To utilize the Evidence-based medicine and the method of systematic analysis. The Meta-analysis of the multipdate of the literature can lead our to know that present the situation of the Randomized -Contorlled-Tirals of the Chinese traditional medicine.Objectives: To assess the safety and efficacy of the Chinese traditional medicine that it helps the climacteric syndrome. To provide the current randomized evidence.The Methods: The Cochrane systematic review method was used to evaluate the matched-control literatures are those published in the civil. To investigate the clinical effect of TCM that it helps the climacteric syndrome. Literature-retrieved data: CBM during 1978-2007 years.CNKI Web during 1994-2007 years. and CQVIP during 1989-2007 years. And manual retrieval collection result publication literature and tracing retrieval related summary, paper reference. In addition, we tracked down the reference lists of papers related to the climacteric syndrome. We included all completed uncompounded truly randomized trials (RCTs) about TCM for the climacteric syndrome. Two authors independently assessed the methodological quality of studies and extracted datas. Discussion or the third person when needed resolved the disagreement. Datas are analyzed with RevMan 4. 3 analysis software supplied by Cochrane centre.Results:We identified 14 completed RCTs, one experiment gazes, stochastically, double blind, the double simulation parallel comparison for front clinical, two central research, is the high grade research, -odd 13 for low quality researches. The showing specifically stochastic method and assigns the hideaway method, In which only 1 mentions uses single blind method, Others have not used blind method. The elimination intervention measure one literature which uses for the injection,we rejected one research about the acupuncture and TCM of treatment groups. Is selected 13 researches to make the Meta- analysis initially. The Meta-analysis result showed that, Seven use the Chinese native medicine to take the treatment group compared with the Western medicine the research research non-uniformity examination:the OR Q=5.82,df=6,P=0.44,I~2=0%.the RR Q=4.58,df=6,P=0.60,I~2=0%.Six use the acupuncture and moxibustion to take the treatment group compared with the Western medicine the research non-uniformity examination:the OR Q=1.93,df=5,P=0.86, I~2=0%. the RR Q=1.83,df=5,P =0.87,I~2=0%.Because of P>0.10,I~2=0%, may think the not non-uniformity, Chooses the fixed effect model to calculate its merge statistics. The Meta-analysis effect size merge result showed that, Seven use the Chinese native medicine to take the treatment group compared with the Western medicine the resarch curative effect analysis:the OR was 0.28, 95% CI[0.17,0.45], Z=5.21, P<0.00001; the RR was 0.32, 95% CI[0.21,0.50], Z=5.13,P<0.00001.Six researches of the acupuncture and moxibustion of treatment groups compared with the Western medicine,the OR was 0.13, 95% CI[0.05, 0.35], Z=4.02, P<0.0004. the RR was 0.15, 95% CI[0.06, 0.38], Z=4.01,P<0.0001.Conclusion: Via the Meta-analysis result, there are some effect of TCM treating climacteric syndrome. But if there were more high quality articles about TCM treating climacteric syndrome, the causality of this article will be more intense.