Mulberry Leaves Water-soluble Chemical Composition

Rail fans Mulberry synonym for a Sankoh(Morus albaL.) Leaves.Mulberry in the ancient medicinal value has been recognized by physicians and attention,and its role in the "Compendium of Materia Medica" are documented in books such as Chinese medicine practitioners believe that mulberry leaves Meitian,sexual-winter can Liquidation liver cong ears,calm nerves,moistening lung,clearing heat,cough,Qualcomm joint.The genus is hypoglycemic,lower blood pressure,anti-bacterial and anti-virus and other biological activity. Modern pharmacological research that leaves inhibited hyperglycemia,with the prevention and treatment of diabetes.In order to better clarify its hypoglycemic material foundation,we are using polyamide column chromatography silica gel column chromatography,HSCCC chromatography and other methods.Mulberry leaves from the ethanol extract of three isolated compounds,which are butanol layer of a compound isolated from the ethyl acetate laver isolated two compounds,a chemical and 1 H-NMR,13C-NMR,IR,and other modern equipment comprehensive analysis identified as quercetin(Ⅰ),Quercitrin-3-O-β-D-glucosaminidase (Ⅱ),β-daucosterol(Ⅲ).β-daucosterol which for the first time found from mulberry leaves.To further clarify pharmacodynamics material foundation laid a solid foundation.This study's major findings are as follows:Physical and chemical identification and the integrated analytical spectroscopy, identified isolated from the leaves of the three compounds were isolated structure,whichβ-daucosterol found for the first time.The experimental quercetin and quercetin-3-O-β-D-glucosaminidase as flavonoids,has an important role in pharmacology.Apart from an expectorant,cough,asthma,such as effectiveness,lower blood pressure,strengthen capillary resistance,reduced capillary fragility, hypolipidemic,hypolipidemic,expansion of coronary artery,coronary blood flow,and other enhanced role.Adjuvant treatment can be used for the Coronary heart disease and hypertension.