Polygonatum Extract Capsule On Postprandial Blood Glucose In Clinical Research,

Review of this paper is divided into two parts and clinical research. The literature review, including single herbs treatment of diabetes research progress and Polygonatum odoratum progress of the modern research, clinical research Polygonatum odoratum extract capsules postprandial blood glucose for diabetes Clinical study of the effects.Single Herb progress in the treatment of diabetic research including clinical research and experimental study. Clinical research focuses on the single Chinese herb in the clinical treatment of diabetes mellitus; experimental study focuses on the single Chinese herb effective research and the chemical constituents of the mechanism of the study. Sheets Herb hypoglycemic mechanism has multi-channel, multi-channel characteristics, is a high-performance, low toxicity, but also the prevention and treatment of complications drugs for the prevention and treatment of diabetes has practical significance, and it is very much the advantages and Research and Development value.Polygonatum odoratum modern research focuses on the progress odoratum used in the ancient Chinese literature studies; Polygonatum odoratum of herbs by the four gas Five and biological characteristics of modern medicine on the chemical composition of Polygonatum odoratum, and the role of pharmacological studies; Polygonatum odoratum active ingredient in the compound and the application of clinical diabetes. Polygonatum odoratum polysaccharide Polygonatum odoratum is the main active ingredient, the use of polysaccharide hypoglycemic effect the prevention and treatment of diabetic significance, and the Yuzhu with great prospects of development.Postprandial glucose in patients with diabetes is the cause of the increased insulin sensitivity decreased, increased illness and could lead to serious complications one of the main reasons, the incidence of diabetes in the process occupies an important position. How effective control postprandial hyperglycemia of diabetes and its complications is an important measure. The purpose of this research: To observe the Yuzhu extract on the impact of postprandial glucose whether it has immediate effect and Yuzhu hypoglycemic possible hypoglycemic mechanism for the clinical application and provide the basis for reference. Methods: Test 1: Select from the wards of the 60 cases of diabetic patients were randomly divided into two groups, namely high-dose group and low dose groups, each with 30 patients. High-dose group were given four Yuzhu extract capsules (equivalent to 30 grams of Health drug Yuzhu), low-dose group were given two Yuzhu extract capsules (equivalent to 15 grams of Health drug Polygonatum odoratum). In patients with impaired fasting glucose control in 12 mmol / L within the premise of the existing treatment, the patients were taking a fasting Yuzhu extract capsules. Test 2: choose another 30 healthy subjects for the control group, for four Yuzhu extract capsules (equivalent to 30 grams of Health drug Polygonatum odoratum). Before and after treatment with monitoring the general situation, fasting plasma glucose and postprandial glucose two hours. This study used statistical software SAS8.2 statistics, the measurement data using t-test, count information with the X2 test. Results: high-dose group after treatment to reduce blood sugar margin, and before treatment showed no significant statistical difference (P> 0.05); low-dose group after treatment margin increased blood sugar, and the treatment showed no significant statistical difference (P> 0.05) after the two groups of blood glucose margin no significant statistical difference (P> 0.05); normal blood sugar control group after treatment had no significant changes in the margin, and the treatment showed no significant statistical difference (P> 0.05). High-dose group decreased 2 hPG trend. Conclusion: high doses of Yuzhu extract capsules have lower blood sugar in diabetic patients with postprandial trend, especially for heat-Qiyinliangxu and more obvious effect of low doses of Yuzhu extract capsules did not lower blood sugar in diabetic patients with postprandial Trends; Yuzhu extract capsule on healthy volunteers did not affect the basic blood sugar.