| Objective: By epidemiology and Syndrome related research, clear non-traumatic necrosis of the femoral head incidence characteristics and study pathogenic factors related to the development trend. Statistic and analyze Syndrome and epidemiological aspects of the relevant factors for the femoral head Necrosis of the prevention, diagnosis and treatment.Methods:1,The non-traumatic necrosis of the femoral head in patients with hospital patients for investigation and the gathering of the general incidence of patients, which include: age, gender, occupation, etiology, clinical course, single bilateral disease, and stages.2,The collection and analysis of non-traumatic necrosis of the femoral head in patients with the clinical data, in accordance with the patients symptoms, signs, Tongue, pulse, the combination of physical examination, and TCM type.3,Samples of the general description and relevance of the research; The etiology and development of a statistical analysis of trends; Syndrome and the clinical course, correlation analysis carried out in stages.Results: 1,Descriptive epidemiology:A total of 555 cases of patients (878 hips), the average age of 42.06 +12.46 years old, male to female ratio 2.4:1, with an average course of 15.86+2.83 months, the unilateral 227 cases (40.9%), bilateral 328 cases (50.1% ), MRI hip Statistics 522, 407 bilateral hip disease, accounting for 78.0%, ARCOI stage 120 hips (13.7%), ARCOII stage 402 hips (45.8%), ARCOIII stage 265 hips (30.2%), ARCOIV stage 91 hips (10.4%).2,Associativity research:The incidence of female to male age difference was significant (P<0.01). Clinical course and gender no correlation (P>0.05), age of onset were positively correlated (r=0.167, P<0.01), and career without correlation (P>0.05), single incidence of clinical course of bilateral was a significant difference (P<0.01). Bilateral associated with single-gender no correlation (P>0.05), age at onset of single bilateral was a significant difference (P<0.05). ARCOⅠstage of bilateral incidence was more than other periods (P <0.05), and ARCOⅣthe age of onset of a period was bigger than the others (P <0.01), and ARCOⅣof the clinical course was longer than other periods (P<0.01).3,Aetiology research:Alcoholic 216 cases (38.9%), Steroid 218 cases of (39.3%), alcohol + steroid 20 cases (3.6%), 101 cases of unknown etiology (18.2%). 1991 to 2000 in alcohol and steroid of a cause than with the 2001 to 2007, there were significant differences (χ2=16.183, P<0.05), steroid gradually increased for reasons. Unknown clinical course than other leader were significant differences (P<0.05).4,Syndrome research: On a sample of 143 cases Syndrome type, collaterals block in 28 cases (19.6%), 54 cases of liver and kidney deficiency (37.8 per cent), Phlegm stasis 61 cases (42.7%); TCM Syndromes no correlation with the clinical course (P>0.05); ARCOII period to permit Phlegm stasis mainly with other syndromes was a significant difference. ARCOIV period to permit mainly liver and kidney deficiency, and other stages was a significant difference (P<0.05).Conclusions: 1,The incidence of the general topic description of the findings reported in the literature associated with the basic agreement, mainly to young people, more male than female, more bilateral disease.2,The incidence of female is longer than male age. The longer the age of onset, clinical course the greater. The period of ARCOⅣsignificantly change the clinical course long period. Bilateral ARCOⅠincidence to other periods of was high (85%).3,Steroid and alcohol in the proportion of pathogenic factors has changed. The steroid of necrosis of the femoral head has been gradually over alcohol.4,Syndrome is associated with the stages. ARCOII period to permit Phlegm stasis was main. ARCOIV certification period was mainly to liver and kidney deficiency. |
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