Integrative Medicine "three Stage" Therapy For Nephrotic Syndrome

Objective:Observe the clinical curative effect the Chinese herbal medicine and Western Medicinetreatment of"three stages"s treat the NephroticSyndrome providing science foundation forthe clinical application of the Chinese herbal medicine"three stages"s therapy.Methods:The sufferer, who choose to 60 cases kidney Medicines diagnose to NephroticSyndrome,is divided into "three stages"s of the Chinese herbal medicine match Prednisone rapyset(treatment group) and the Prednisone to match with heteropathy set(control group) to thedisease therapy, each 30, two sets of sufferer's ages, sexes, course, conditions, clinicalsymptom etc. learned a processing to all don't show significant difference through astatistical treatment (P＞0.05); method of treatment, the treatment set first stage Chineseherbal medicine cures for 2 weeks, being divided into Deficiency of a liver and kidney yin,the blood stasis and hot stagnant type or Deficiency of Spleen and kidney yang, the bloodstagnant water to coagulate type cure for two weeks;Second stage 8 week Chinese herbalmedicine add Prednisone treatment;The third stage 16 week the Prednisone reduceto stop atreatment;The control group first stage cures to the disease for 2 weeks:Choose diuretic anddecline blood fat medicine, decoagulant etc. to cure to the disease.Second stage Prednisoneand cure to the disease for 8 weeks, Prednisone everyday a morning to take with the 1mg/kg/d, and take adequacy choice western medicine treatment such as diuretic, decoagulantand decline blood fat medicine according to the different condition.The third stagePrednisone reduce to stop to cure for 16 weeks, the Prednisone reduces a quantity methodto cure a set together course of treatment all is 26 weeks, after the trement compare twosets of medical doctor comprehensive the curative effect, Chinese medicine indicationcurative effect, indication integral calculus, albuminuria curative effect, blood plasmaprotein, blood plasma total cholesterol and triglyceride an examination analysis index, andobserve relapse rate post-treatment and relapse a rate of the Prednisone side effect, studyingthe Curat effect of Chinese herbal medicine"three stages"s effect under treatment.Statisticsa processing method, measurement data to average with the root-mean square deviation,matching Gaussian distribution use a T examination.The differential count to relativelyuse chi square examinations;The ranked data uses Radit analysis; hypothesis test unifies anusage double a side an examination, giving the examination statistics quantity and it toshould of the corr P mumber, with P＜0.05 conduct and actionses have already manifeststatistical significance.Results:1,Treatment set treatment nephrotic syndrome for complete remission rate as 50.00%,clinical total effective rate reach to 96.67%;The matched control group complete remissionrate 33.33%, clinical total efficient 80.00%.Was learned by statistics analysis, 2 sets cure in front and back symptom integral calculus to all show significant difference verymuch;(P＜0.01)On the Chinese medicine symptom, the treatment set is efficient to 96.67%,the clinical completely recovered rate is 53.33%, matched control's ising efficient is 86.67%,clinical completely recovered rate 36.67%, 2 sets' curing relatively has already shownsignificant difference in front and back(P＜0.05), Explain 2 sets all an ability is valid to curea kidney disease comprehensive advertise for;Two sets of relatively have already shownsignificant difference(P＜0. 05), The curative effect of explaining the treatment set surpassesa matched control.2,In the different type of syndrome, treatment set yang asthenia the type show an effect toalleviate the rate as 84.21% above, yin asthenia the type show an effect to alleviate the rateas 72.73% above, comparing yang asthenia a type is low, matched control yang asthenia typeshow an effect to remission rate as 66.67% above, yin asthenia type show an effect toremission rate as 58.33% above, also comparing yang asthenia type is low, match "the yangasthenia cures easily, the yin asthenia is difficult to adjust of theories".But interclass thehomology type of syndrome relatively has already shown difference(P＜0.05), The curativeeffect of expressing the treatment set surpasses a matched control.3,Two sets of medicine all the ability improves related and clinical symptom in certaindegree, but the treatment set result show significant (P＜0.05), the treatment set's theCushing's syndrome, caput femoris changes, erupt an infection, Withdraw to stop reactionetc. the Prednisone side effect is obviously low in the matched control(P＜0.05). Cure onetrack after year with visit, observe two sets of to relapse a rate comparison, explain atreatment set to surpass a matched control obviously.Conclusions:"Three stages"s of the Chinese herbal medicine match Prednisone cures a nephroticsyndrome is certain about curative effect, to suffice embody the Chinese medicine theorythe concept of viewing the situation as a whole and the distinguishing feature ofdetermination of treatment based in pathogenesis obtained throu-gh differentiation ofsymptoms and signs, also outstanding the Chinese medicine discrimination disease anddialectics combine together of advantage.Affir med the comprehensive certificate functionof the Chinese herbal medicine treatment nephrotic syndrome and exertive beneficialfunction in raise Prednisone curative effect, and ease a Prednisone treatment obviouslybehind the side effect appeared, thus in the aspects of preventing and curing complications,raising a sufferer to bear Prednisone to be subjected to sex and reducing disease to relapseetc.