Purpose: Study Gnyuling Jiaonang's influence for the IL-1, IL-8 and TNF-αexpression in the bone model serum of the arthritis domestic rabbit more. Method: Adopt the Hulth builds the mold method establishment OA model, build after the mold a muscle to note penicillin for a week and prevent°from infection, infuse stomach after 4 weeks, take serum after 6 weeks, measurese IL-8, IL-1 and TNF-αlevel. Result: The IL-8, IL-1 and the TNF-αare obviously low at the model matched control in the Chinese herbal medicine set model serum, the difference shows Zhao,. (P<0.05) Conclusion: The Chinese herbal medicine Gnyuling Jiaonang more to the IL-1, IL-8 and TNF-αin the bone model serum of the arthritis domestic rabbit's expression to have to obviously repress a function and contain good treatment function to the bone arthritis. |