| 【Objective】Cancer of colon is one of the most common malignant tumors of digestive tract. Observing the tongue pictures of colorectal cancer patients side effect quality of life of the chemotherapy in order to guide clinical therapy predict the prognosis【Methods】Clinical research 1 : Observing the changes of tongue pictures of 62 colorectal cancer patients before and after the chemotherapy.【Results】Research 1 demonstrated that before chemotherapy, light red tongue and crimson tongue were the most common ones, accounting for 37.10 % and 30.65 % , in comparison with the purple tongue after chemotherapy, accounting for 33.87%.Purple tongue would get worse after chemotherapy .It was common that crimson tongue turned into purple after chemotherapy. Tongue body was usually normal before chemotherapy, while after chemotherapy tongue with ecchymosis and tooth-marked tongue gained advantage, accounting for 33.87% and 11.74%.Colour and shape of tongue showed significant difference before and after chemotherapy (P<0.05,P<0.01).Moist tongue coating accounting for 43.55%before chemotherapy, while greasy tongue coating 40.32% after chemotherapy . There was no difference of tongue texture before and after chemotherapy (P>0.05).Thick and light yellowish tongue coating gained advantage before and after chemotherapy. Thickness of middle tongue coating showed extremely significant difference (P<0.001).Research demonstrated that there was significant difference between the two groups in leucopenia, gastrointestinal symptoms and peripheral nerves. We draw a conclusion that Huachansu combined with chemotherapy could alleviate the side effect of chemotherapy. There was also significant difference between the two groups in health conditions, fatigue, mood, nausea, vomiting, anorexia and diarrhea (P<0.05). We could further confirmed that Huachansu could improve the quality of life .After chemotherapy,tongue with ecchymosis and purple tongue covered the highest proportion .There was sifnificant difference between the two groups in fur character, colour and thickness (P<0.05).Huachansu could alleviate the greasy tongue coating of the chemotherapy patients .The another result expresses thin white the cancer certificate of the tongue a sufferer a more difficult persistence completion chemotherapy.Purple tongue, deep tongue and pale red tongue, red deep tongue compare, these sufferers are extremely vice- to chemotherapy to respond sensitive, appearing a digest way reaction easily and surroundings the white cell descend, with the result that hard persistence completion whole distance chemotherapy.Clinical fruit 2 manifestation in research Erh-chieh after observing discovering chemotherapy ex- sufferer with the spleen annoys stagnation of qi falsely for seeing have 40.32% much, but the chemotherapy is behind still being with the spleen annoys stagnation falsely for having 46.77% more, and chemotherapy annoy anemia falsely of the case has 17.74% less.(P>0.05), chemotherapy in front and back the Chinese medicine certificate type didn't show difference. Regard purple tongue as principle observe a chemotherapy in front and back a Chinese medicine certificate to wait, can see a chemotherapy in front and back and all with the spleen annoys stagnation falsely for lord, and the chemotherapy increase 81% behind, it is thus clear that the relation of purple tongue and spirit stagnation is bigger.The chemotherapy ex- purple tongue set and not- purple tongue set compare, the symptom which has covariance to learn difference has:Languid and tired, the thirsty swallow dry.(P<0.05)Have the symptom that the covariance learns meaning with the related degree of the purple tongue from big arrive small is:The thirsty swallows dry, languid tired, the complexion is dark, the complexion white is only white, suffering from insomnia, fidgety irascibility. Purple tongue set after the chemotherapy compared with the not- purple tongue set, the symptom which has covariance to learn difference has:The thirsty swallows dry, legs anasarca.(P<0.05)The covariance learns the symptom of the meaning and the related degree of the purple tongue from big arrive small is:The thirsty swallows dry, have a poor appetite, the ennui is tired, lazy speech.Research 3 demonstrated that there was significant difference between the two groups in leucopenia, gastrointestinal symptoms and peripheral nerves. We draw a conclusion that Huachansu combined with chemotherapy could alleviate the side effect of chemotherapy. There was also significant difference between the two groups in health conditions, fatigue, mood, nausea, vomiting, anorexia and diarrhea (P<0.05). We could further confirmed that Huachansu could improve the quality of life .After chemotherapy,tongue with ecchymosis and purple tongue covered the highest proportion .There was sifnificant difference between the two groups in fur character, colour and thickness (P<0.05).Huachansu could alleviate the greasy tongue coating of the chemotherapy patients . 【Conclusions】Research demonstrated most colorectal cancer patients got purple tongue and tongue with ecchymosis, which was the same with records and it would get worse after the chemotherapy . Cancer patients are in a qi stagnation and blood stasis condition .Chemotherapeutics Tend to damage the spleen and stomach, inhibit marrow and cause liver and kidney deficiency, insufficiency of yin-blood, dryness in blood. It is considered in Traditional Chinese Medicine that protracted disease intruding into collaterals can result in deficiency, blood stasis and aggravate qi stagnation and blood stasis.So we can add some herbs of reinforcing qi, activating blood flow and promoting qi circulation, such as Huangqi, Dangshen, Baizhu, Fuling, Danggui, Chuanxiong, Taoren,Honghua,Danshen, Chishao,Sanqi, Yujin, Yuanhu, Ruxiang, Moyao,Sanleng, Ezhu,Chuanshanjia,Zaoci,Zelan, Quanxie, Tubiechong,Shuizhi and so on . Herbs of invigorating spleen and replenish qi can relieve the side effect of gastrointestinal tract during the chemotherapy, protect the function of liver and kidney, improve immune function and protect hemogram .During the chemotherapy intermissions, we should combine with herbs of activating blood flow and eliminating stasis such as Ezhu,Danshen,Sanqi,Niuxi and so on to anti-coagulation, anti-tumor, improve microcirculation and anti-metastasis .The main tongue body was plump and tooth-marked tongue after chemotherapy .The main tongue coating was light yellowish, thick and greasy tongue coating, and the changes in the middle gained advantage. This was related to the damage of chemotherapeutics to the spleen and stomach.The chemotherapy can make blood ecchymosis from the tongue elephant the certificate wait to aggravate, will also increase the occurrence of blood ecchymosis , or make blood ecchymosis the certificate aggravate.See fat and big tongue, tooth mark tongue, ecchymosis spot tongue a sufferer a more difficult persistence completion chemotherapy from the tongue form.The chemotherapy is hot on the pathogenic quality evil, chemotherapy from inside but spread an outside, harm and annoy blood, internal organs much.Past falsely the certificate pierces through always in the tumor to be taken bad with treatment of the whole processeses present also for main antinomy, should also value blood for cent in the meantime of ecchymosis .After accepting a chemotherapy, part of pale red tongues convert with purple tongue toward the crimson tongue, making purple tongue, ecchymosis spot's comparison of the tongue increment.A part of normal tongue forms change into tooth mark tongue, original of thin small tongue disappear.Express a chemotherapy a machine body to appear spirit blood saliva for period the metabolism abnormality of the liquid in the eyes of the Chinese medicine, take annoying the blood ecchymosis and water liquid stagnation as the vital link of disease machine.The variety of the tongue elephant in the chemotherapy process, also the body wears the reaction appearance of chemotherapy's harm to machine body degree and machine body now.The tongue-coating increases thick, become Huang, to some extent reflected chemotherapy opportune moment's excessiveness of the body should arouse appearance, the Chinese medicine can pass to help stomach spirit, dispeling in addition to wet muddy method, make should arouse respond to positive regulate of direction development.The tongue color becomes purple with the appearance of machine body circulatory system related, the Chinese medicine thinks the spirit blood ecchymosis is very disadvantageous in the machine body's repair to harm, even is the key main factor of disease occurrence.Therefore wait diagnosis according to disease machine analysis and certificate of Chinese medicine, adopt benefit spirit to live blood and manage spirit to live blood's etc. reasonable of go blood to turn a ecchymosis method, is the valid measure that a repair ability and anti- which strengthen a machine body hurts an ability probably.We are after observing discover among them with ennui tired, the ennui is lazy to talk, thirsty swallow stem, dizzy and giddy etc. symptom to see at most;Pass dialectics analysis, with falsely certificate is lord, it familiar certificate type one by one in order for annoy yin two falsely, debility, spirit blood two falsely, yin falsely and sun falsely certificate;Pathological changes internal organs regard spleen , kidney two dirty damages as principle;Can clip phlegm and clip ecchymosis after the chemotherapy in and clip the dialectics.See a fidgety stuffy etc. substantial evidence of the irascibility, chest may also.Large intestine cancer after the chemotherapy with falsely certificate is lord, the truth or falsity mixs up, and annoys yin two falsely the certificate waits for the most familiar certificate, curing should with the benefit spirit keep yin for main principle.Matching with the Chinese herbal medicine treatment can make stronger curative effect, alleviating symptom, reducing the side effect of the empress of the chemotherapy, controling tumor to relapse to transfer.The control accumulates water, raising the machine body immunity function to strengthen an anti- disease ability and Improve life quality.Was discovered by observation the chemotherapy in front and back purple tongue all swallows with thirsty dry have relativity, malignant tumor not on sending falsely a certificate is a truth or falsity to mix up of certificate.The chemotherapy is poison for heat, hot poison harm yin , with as for appear thirsty to swallow dry symptom, the clinical under medical treatment can consider to add to repair yin medicine if living ground, shihu , bulb of lily, jade bamboo, turtle plank, wheat winter etc..This symptom has relativity with purple tongue, purple tongue for stagnation of qi and blood ecchymosis with the result that, but stagnation of qi and blood ecchymosis usually can with the result that the sweat stops, the sweat stops but appears thirsty to swallow dry.Therefore we can pay attention to the occurrence of sufferer's this symptom when the tumor beginning deliver, defending to suffer from in not yet, and should even notice the circumstance that it appears with purple tongue in the meantime.Was discovered by observation the chemotherapy in front and back purple tongue all swallows with thirsty dry have relativity, malignant tumor not on sending falsely a certificate is a truth or falsity to mix up of certificate.The chemotherapy is poison for heat, hot poison harm yin , with as for appear thirsty to swallow dry symptom, the clinical under medical treatment can consider to add to repair yin medicine if living ground, stone hu , bulb of lily, jade bamboo, turtle plank, wheat winter etc..This symptom has relativity with purple tongue, purple tongue for stagnation of qi and blood ecchymosis with the result that, but stagnation of qi and blood ecchymosis usually can with the result that the saliva stops, the saliva stops but appears thirsty to swallow dry.Research demonstrated that Huachansu combined with chemotherapy could alleviate the side effect of chemotherapy .There was also significant difference between the two groups in health conditions, fatigue, mood, nausea, vomiting, anorexia and diarrhea. We could further confirm that Huachansu could improve the quality of life. EORTC QLQ-C30 could further confirm that Huachansu could improve the quality of life. In a addition, Huachansu could reduce purple tongue and ecchymosis of the chemotherapy patients .Huachansu could alleviate the greasy tongue coating, yellow fur, thick tongue coating of the chemotherapy patients.Do the content of"certificate" and life quality a comparison, not difficult discover both have many common place.But the quality questionnaire of the doctor life sometimes neglects easily some in Chinese medicine's eyes very important symptom such as tired have no dint, perspire an etc..Come up to say from a certain meaning, the certificate is from the Chinese medicine angle to a kind of special understanding and judgment which exists quality.The Chinese medicine dialectics is a dynamic state process, but the dialectical theory cure to then monitor foundation that live quality's variety in the dynamic state up, give regulatory process at any time.So we are clinical medium can will both the organic knot put together, real attain advantage to repair with each other, win doctor to combine. |
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