Skullcap Herbs Fingerprinting And Chemical Composition Determination

Scutellaria baicalensis Georgi is one old and well-known drug in traditional Chinese medicines and widely used for treatments of bronchitis,hepatitis,tumors,and inflammatory diseases Recently, the international study Scutellaria more and more because of its various pharmacological effects.This paper includes two parts:The first part introduces the herbal medicine origin chemical components active ingredients determination,and give a brief description of Chinese herbal medicines HPLC fingerprint chromatogram the relationship between Chinese herbal medicines pharmacological effects and inorganic elements.The second part covers five aspects:1. Research the chemical components of Scutellaria: It separates baicalin and confirms the structures through the method of UV IR MS.2.Determinate the effective ingredients of Scutellaria:It determinates flavonoids by UV and baicalin by HPLC.This gives the factory a guide in choosing Chinese herbal medicines.3.Study the extraction process of Scutellaria: It selects the best one by Orthogonal Test and purificate flavonoids referring to the 2005 version Pharmacopoeia.This provides the factory with production basis .4.Research the fingerprint chromatogram of Scutellaria: It builds up the fingerprint chromatogram of different origin Scutellaria by HPLC.Yhis provides the basis for its quality control.5.Analyse inorganic elements of Scutellaria: It determinates 23 inorganic elements of Scutellaria by ICP-MS.This helps to explore the relationship between Chinese pharmacodynamics and inorganic elements.6.Confirmate the structures of the compounds of Scutellaria: Confirmate the structures of the compounds by LC-MS.