Clearing Away Heat And Promoting Blood Circulation Method To Prevent Unstable Angina (chest Pain) In Patients With Cardiovascular Events And Restenosis After Ptca In The Randomized Controlled Clinical Trials

[Background]Coronary atherosclerotic heart disease(CHD) is a clinical familiar andmultiple disease. Unstable angina pectoris (UA) is in the center position of CHD. Acute myocardial infarction (AMI) attack and restenosis (RS) after PTCA is always the main factor to affect its prognosis. At present the fundamental clinical cure principle is "YIQI HUOXUE, XUANBI TONGYANG". This research puts forward the treatment principle of " Yangyin Qinre Huoxue" to treat UA and prevent and treat RS after PTCA not only on the basis of modern mechanism ( the inflammatory reaction, the formation of thrombus) , clinical characteristics and pharmacology experiments of UA but also on the basis of clinical documental reports. In this research we select MaiLuoNing as representative drug to carry out theory and clinical practice study as well as to investigate the clinical curative effect and the possible function mechanism of the principle "Yangyin Qinre Huoxue" to cure UA.[Purpose] Primarily evaluate the position and function of the method "YangyinQinre Huoxue" to prevent UA (XiongBiXinTong) from taking place cardiovascular event and RS after PTCA.[Methods] This research uses the method of random comparison. In the first part 40cases of UA patients in hospital are divided into two groups by random. One is matched control group(standard curing set) and the other is treatment group (standard curing +MaiLuoNing set). Each group has 20 cases. The aim is to observe the frequency of cardiovascular events. In the second part patients who have received PTCA are divided into matched control group ( standard curing set) with 9 cases and treatment group (standard curing +MaiLuoNing set) by random. Six months after patients out of hospital we followup them and recheck their coronary atherography(CAG) for observing RS occurrence rate.[Result] The first part result is that after curing the treatment group's clinical total effective rate is 80% and obvious effective rate is 30%. The treatment group obviously surpasses the matched control group (P<0.05). The treatment group and the matched control group respectively have 2 and 4 cases with emergency call PTCA. In the second part the two groups did not take place angina that obviously disappear or alleviate after PCI.