After Studying Traditional Chinese Medicine Kang Xinping And Its Decomposed Formulas Rabbits In The Myocardial Monophasic Action Potential

Objective To observe the effects of kangxinping and its removed on monophasic action potential (MAP) in the rabbit heart. To study whether its antiarrhythmia or not , and the possibility of its mechanism.Methods Heart monophasic action potential recorded technique was adopted in the study .24 healthy rabbits were divided randonly as kang xinping , NS , Chaifang (B and Z ) . To observe the changes of MAP before their adminiation and after 30 mintues ,60 minitues ,90 minitues, 120 minitues of their admitiniation. The guidelines: the duration of MAP at 50%(MAPD50) and 90%(MAPD90) repolarization. Amplitude of (MAPA) , effective refective period (ERP), and the ratio of ERP/MAPD90. Result Chinese traditional medicine compound kangxinping shortened the rabbit heart MAPD90 from its (86.21 ± 10.10. 34) ms to (72.53 ± 6.03) ms (n=6, P<0. 05) ; reduced MAPA (23. 04 ±3.07) ms to (7. 73 ±1. 77)ms(n=6,P<0.05) and prolonged the ratio of ERP/MAPD90 from(0.8503 ± 0. 0014) to(0. 9824 ± 0. 0008) (n=6, P<0. 05) ;Which is independence of time . Otherway, its MAPD50 ,ERP and the groups of NS and Chaifang had no significantly change. Statistics paired samples T-test was adopted, and with its descriptives X±S. Conclusion kangxinping has its effect on antiarrhythmia . Maybe...