| Objective: To test the effect of Radix Astragali seu Hedysari Decoction for warming the Middle Energizer (RA) on SP and VIP in the ileum of rats with deficiency of spleen-yang.The purpose of this researcn is to explain the mechanism that the decoction of RA can remedy the deficiency of spleen-yang and explore rudimentarily the relationship between deficiency of spleen-yang and NEI and the role of RA. Methods: First,we divided the rats into four teams at random, the team of sufferer.the team of natural recovery, the RA team plus a normally fed team.Each team included ten members. To copy the model of spleen-yang deficiency, we have successfully made all the rats except the normally fed team suffer from diarrhea.The rats of each team were poured with peculiar decoction for 14 days.After all the things finished,we -took ileum of the rats to test the change of the matter of SP and VIP.Results: Compared with the normally fed team(P<0.01),the contents of SP in the team of sufferer were obviously raise,and the contents of VIP were clearly decreased. It has showed that the disorder of gastrointestinal hormones and NEI exists in the rats of sufferer.In the RA team,the contents of SP and VIP obviously returned to normal,compared with the team of sufferer(P<0.01,P<0.05),and compared with the normally fed team there is no obvious statistic difference (P>0.05). The contents of SP and VIP in the natural recovery team were clearly different from the normally fed team(P<0.05,P<0.01). Conclusion: This research shows that the decoction of RA can obviously improve the symptoms of the rats with deficiency of spleen-yang, make the contents of SP decreased and make the contents of VIP raised in ileum of rats .It may be one of the treatment mechanism that the decoction of RA can return the motion and absorption of stomach-intestine to normal by regulating the neuro-endocrine function. At the same time.the decoction of RA can better the immunologic function of organism. |
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