Acute Phase Of Stroke Syndromes Correlation With The Underlying Disease And Nerve Function Impairment

Objective:To investigate the correlation between background diseases and neurologic impairment with the distributions of TCM syndromes in patients of stroke acute stage by analysis TCM syndromes in 56 patients with the disease. Method: 56 patients were diagnosed into six basic syndromes according to Diagnostic Standards of Syndrome Differentiation on Apoplexia. Divide them in two groups basis their degree of neurologic impairment (scores of NIHSS) and background diseases such as hypertension, diabetes, CAD( Coronary Artery Disease) and past stroke history. Investigate the difference and test it in statistical method. Results: 1. In the 56 cases in acute stage of stroke, the occurring frequency rate of wind syndrome is 85.7%, the highest in the 6 kinds of mainly syndromes. The rate of fire syndrome and phlegm syndrome is 57.1%,lower than the wind. 2. In the combinative styles of syndromes, the occurring frequency rate of the combinant of 3 syndromes is 33.9%, the highest. the rate of one syndrome style and the combinant of 2 syndromes are 21.4% and 19.7%, much lower. In the patterns of the combinant of 3 syndromes, 9 cases of wind syndrome + phlegm syndrome + fire syndrome pattern is 47.4% of the combinant of 3 syndromes and 16.1% of all the cases, these is the highest rate in all the combinative styles of syndromes. 3. Comparing with the cases without hypertension history, the cases with hypertension have higher risks of Yin-deficiency and Yang-hyperactive syndrome, wind syndrome and blood-stasis syndrome. On other hand, they have a lower occurring rate in fire syndrome, phlegm syndrome and Qi-deficiency syndrome. Their difference in Yin-deficiency and Yang-hyperactive syndrome has a remarkable statistical significance (p<0.05). Comparing with the cases without diabetes history, the cases with diabetes have a higher rate in occurring of wind syndrome and phlegm syndrome, at the same time, they have a lower occurring rate in other four syndromes. It must to be mentioned that, the difference in this two group have no remarkable statistical significance. Group with a history of CAD has a much more frequency of the occurring in wind syndrome, phlegm syndrome and blood-stasis syndrome. The difference in blood-stasis syndrome has a remarkable statistical significance (p<0.05). In the occurring rate of fire syndrome and Qi-deficiency syndrome, Group with CAD has a lower rate. The occurring rate difference between these two groups in Yin-deficiency and Yang-hyperactive syndrome is not obvious. 4. With a history of stroke, the cases have a higher occurring rate in wind syndrome and blood-stasis syndrome, meanwhile, they have a lower occurring rate in other four syndromes. The lower occurring rate in Qi-deficiency syndrome is obvious, though the difference of the diverse group based on a history of stroke is unremarkable. 5. Worse neurologic impairment cases have a higher occurring rate of all the syndromes except Yin-deficiency and Yang-hyperactive syndrome, they have a lower rate in the occurring of Yin-deficiency and Yang-hyperactive syndrome. The differences of these two groups have no remarkable significance after statistical treatment. Conclusion:Phlegm syndrome, fire syndrome especially wind syndrome is the most important TCM etiological , pathogenesis factor and syndrome appearance in the acute stage of stroke. The background diseases do a notable influence in the distributions of TCM syndromes in acute stage of stroke. A stroke patient with hypertension have higher occurring rate of Yin-deficiency and Yang-hyperactive syndrome. Stroke patients with hypertension have higher occurring rate of Yin-deficiency and Yang-hyperactive syndrome. Stroke patients with a history of CAD have a significant high occurring rate in blood-stasis syndrome. Re-stroke patients have obviously lower occurring rate in Qi-deficiency syndrome but the difference has no remarkable statistical significance. Worse neurologic impairment cases have a higher occurring rate of the syndromes and the difference has no remarkable significance a...