Gastroesophageal reflux disease (GERD) was the symptoms and complications of contents of stomach and duodenum refluxing to the esophagus. The incidence of this disease was about 5.77%. It was a common disease in our country.This disease was belong to traditional Chinese medicine concepts, such as "acid regurgitation", "acid swallow". This thesis reviewed its etiology, pathologic mechanism, and treatment principles in TCM from ancient books and modern research. We came the conclusion that spleen deficiency and liver stagnation, failure of stomach Qi descend with abnormal flow of stomach Qi were the principal mechanism of this disease. The location of this ailment was in spleen and stomach. It was closely related to the regulation function of liver. This thesis also reviewed its pathogenesis, diagnosis and treatment according to modern science findings. The treatment principles, to strengthen spleen and soothe liver, regulate Qi and descend adverse flow of Qi were established. The principles of how to form the prescription were also been discussed. The treatment principles, to strengthen spleen and soothe liver, regulate Qi and descend adverse flow of Qi might be related to promoting gastric emptying, strengthening the esophageal anti-reflux barrier and expurgation function, or accelerating the repair of esophageal mucous membrane. |