Yasuji Static Particle Pharmacy Part Of The Study

An'erjing granules is a kind of traditional Chinese medicine combination product which consists of Radix paeonike alba, Radix acanthopanacis senticost and eight other herbs with the effects of nourishing the blood, suppressing the liver-yang and nourishing the heart to tranquilize the mind .It is indicated for the treatment of Anxiety such as terror or panic , palpitation, insomnia, dreaminess, dizziness. With the guidance of theories of Traditional Chinese Medicine and Pharmacy(TCMP),adopting the modern pharmaceutical research idea and method ,it is manufactured to granules by research and demonstrating and pre-test. The process route is designed to water-extract and alcohol-extract which is based on the requirement of preparation together with the character of herbs. The research has been screened out the best process conditions with orthogonal method using extracts rate and content to evaluate. The formulation process has been researched the type and dosage of the excipients and process conditions. So the preparation procedure is that the herbs made by processing and extract, separated by high speed centrifugal filter and dried by spay drying and then granulated. At the same time, the quality standard of the drug product for clinical trail has been made and the preliminary stability has been finished. The results indicate that the preparation process is reasonable and practical, the standard is controllable, the quality of the sample is steady on the whole as well.