Hyperlipidemia Phlegm And Blood Stasis Syndrome Type Mechanism

Objective: To explore the form of hyperlpemia and the produce of the phlegm and blood-stagnation by TCM's theory.To study the biochemistry mechanism between hyperlpemia types of the phlegm-stagnation-syndrome and of the qi and blood-stagnation.Method: The serum cholesterol (TC), triglyceride(TG), low density lipoprotein and high density lipoprotein, (LDL-c,HDL-c), apoAl,apoB100,apoClI and apoCIII levels were detemined in 20 patients with hyperlpemia in the phlegm-stagnation-syndrome group and in 20 patients with hyperlpemia in the qi and blood-stagnation group and in 20 healthy people.Result: Compared with healthy group,TG,LDL-c level in patients with hyperlpemia in the plilegm-stagnation-syndrome group significantly increased (p<0.01),TC, apoCin level significantly increased Cp<0.05) , apoC II level significantly decreased (p<0.05) .TC, apoBl00 level in patients with hyperlpemia in the qi and blood-stagnation group significantly increased (p<0.01), TG level significantly increased(p<0.05),HDL-c level significantly decreased(p<0.01), apoAl level significantly decreased (p<0.05) .Conclusion: Phlegm and bloo'd-stagnation are the key reason of hyperlpemia. The increase of TG,TC,LDL-c level is the main characteristic of patients with hyperlpemia in the phlegm-stagnation-syndrome, and followed by the decrease of apoC H level, increase of apoCIII level. The increase of TC, TG, HDL-c level is the main characteristic of patients with hyperlpemia in the qi and blood-stagnation, and folio wed by the decrease of apoAl level, increase of apoBlOO level.