The increased occurrence CO2-pneumoperitoneum can promote peritoneal tumor growth and abdominal metastases after laparoscopic surgery for malignant tumors has been widely noticed in recent years, the mechanism is still unknown and the accepted approach to prevent it is under exploring. The aim of this study is to summarize current research and suggest that improving the acid environment of abdominal and mediating cytosonic acidification from peritonealmacrophages may be a important approach to inhibit peritoneal tumor growth and abdominal metastases in laparoscopic surgery. |