| Objective: To investigate the possible mechanism affecting liver cirrhosis by splenectomy. Methods: Kunming mice (n=90; 20?8g) were randomly allocated to three groups: Gl, splenectomy (n40); (;2, non?splenectomv (n40) ; and 63, normal control (n10). By subcutaneous administration of 20% Cd.1, liver cirrhosis models were established in 61 and G2 groups. After 4th, 8th, 12th and 16th of drug injection, liver pathological changes in mLe w~re studied respectively in comparison witt~i normal group. hollowed by immunohistochemical stainir~igdetection,eg. Mast cell (MC), Kupft抏r cell and Ito cell were counteu under optical microscope. All data was analyzed by using statistical methods. Results: The quantity of MC had significant difference in 4th, 8th between G1 and G2 group (p |
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