Primary Hyperuricemia-related Factors And Tcm Syndrome

Background:Hyperuricemia is a purine metabolic abnormalities diseases, modern research show the disease is closely related with the metabolic syndrome, the literature has confirmed that exogenous feeding purine much factors, endogenous purine 20% metabolic abnormalities factors account for 80%, so besides diet education, improve endogenous metabolism becomes the main direction of treatment. Modern clinical commonly used drugs mainly includes inhibit uric acid is synthesized and promote uric acid excretion two kinds, because the two types of drugs could induce bone marrow, liver and kidney impairments. This study aims to looking for new ideas in solving hyperuricemia in TCM.Objective: Research in this disease and metabolic syndrome, the correlation of various components of the disease involve a comprehensive survey of the risk factors, explore independently of the high uric acid syndromes science research and preliminary treatment principle, to provide ideas for clinical treatment.Methods:(1) access to hyperuricemia hematic disease related literature combining clinical actual situation, formulate a unified cases observation in advance, clinic reserch form (CRF), including patient basic material, hyperuricemia related risk factors, such as syndromes of hyperuricemia. After filling out CRF,we statistics the clinical investigation results.(2) according to TCM syndrome differentiation and treatment, we prescribe drug for four weeks to clear heat and promote diuresis.Compare the blood uric acid results before and after the record drugs.Results:(1) the onset of primary high uric acid acidemia proportion and gender, age, occupation and rest not laws, high purine diet, water quantity deficiency significantly related compare in complications, hypertension, diabetes, cerebrovascular disease, cardiovascular disease, and dyslipidemia, obesity happening more relevant;(2) blood uric acid 476umol/1 numerical, bounded after coronary eent grouping comparison:high, high density protein low, cereal third transaminase is high with more related numerical high blood uric acid; High uric acid family history, high purine diet, exercise not rule and the blood more related numerical low serum uric acid; (3) high uric acid with the hot and humid hematic disease hot and humid license issuing comparison:water quantity deficiency, drinking rate and hot and humid card group more relevant;(4) hot and humid, spleen deficiency, kidney deficiency,qi deficiency syndrome are main syndromes;(5) utilization of drug to clear heat and promote diuresis, treatment of traditional Chinese medicine treatmentresult role four weeks display effect is obvious.Conclusion:(1) we should propaganda the healthy life concept to prevent and treat hyperuricemia, especially for service and administrative personnel:appropriate increase water quantity, reduce the number of eating out, regulating the dietary structure, diet and time, limit alcohol, etc.;(2) in the endogenous insulin resistance,high blood uric acid patients is more relevant than low numerical high group.Remind us, to improve endogenous insulin resistance treatment is more important to these patients.(3) in blood serum uric acid with coronary heart disease incidence of numerical high attention more relevant, hint, heart pumping blood group crowd to is not ill, which lead to prevent the purpose of illness(4) heat and humid is major syndromes, use the drug to clear heat and promote diures, preliminary observations have shown clinical effective, for the next step ZhuZheng theory system formed catch lay the foundation;...