.46 Cases Of Behcet's Disease Clinical Data Analysis

Objective To improve understanding of Behcet's disease, by exploring the clinical characteristic and manifestations.Methods To statistically analyze onset ages, clinical manifestations, system involvement, auxiliary examination, all clinical data of 46 patients who had been hospitalized in China-Japan Friendship Hospital with the diagnosis of Behcet's disease in 13 years was cllcected. Results 46 patients were available for the analysis, in which 27 were males,19 were females with about 1.4:1 ratio. Average onset ages was (31.24±14.34) years. The course duration was (9.28±9.34) years. Behcet's disease occurred in all age groups, the young and middle-aged 35 (76%) patients were primarily,with no difference between men and women patients. The most frequent manifestations at disease onset were oral aphthae (80%) and genital aphthae (22%), followed by skin lesions (11%), fever (7%) and arthralgia/arthritis (4%).22% patients had two or more manifestations at disease onset. The most frequent manifestations were oral aphthae (100%)and genital aphthae (80%), followed by skin lesions (76%), which were described as erythema nodosum(48%), pseudo-folliculitis (26%), and lower limb erysipelas (2%), followed by positive pathergy test (54%), arthralgia/arthritis(50%), inflammatory ocular disorders (43%), fever (37%), digestive system involvement(15%), big vascular impairment(9%), neurological damage(4%) and epididymitis(2%).76% patients presented skin lesions, and most of them were males (57%vs20%, P=0.010).54% patients presented positive pathergy test, and most of them were males (43%vs 11%, P=0.002). No significant sexual difference had been found of other clinical manifestations. Conclusion Behcet's disease occurred in all age groups, multiple organs and systems could be involved, with diversity of clinical manifestations and significant difference of skin lesions and pathergy test between men and women patients.