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The Clinical Research Of Shenqifuzheng Injection In Improving The Heart Damage Caused By Adriamyc

Posted on:2011-11-04Degree:MasterType:Thesis
Country:ChinaCandidate:H Z ZhangFull Text:PDF
GTID:2194330332474630Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective:To observe the Shenqifuzheng injection to improve the heart damage caused by the clinical efficacy. Methods:will be incorporated into the standard 40 patients were randomly divided into two groups to observe the group of 20 patients in control group 20 cases. Before treatment, observation and control groups was no difference in the basic conditions (P> 0.05).Control group, the use of conventional chemotherapy alone; Observer Group on the basis of conventional chemotherapy was added Shenqifuzheng injection, All cases were observed in six cycles,21 days for a cycle. Observed observed after six cycles and control groups of clinical symptoms and laboratory indicators of changes in check, of which the main observation of indicators of cardiac troponin Results:After 6 weeks of treatment, observation and control groups were ECG heart rate, cardiac function tests showed two groups of patients had decreased cardiac function, but the decline in the observation group than the control group, therapy group, Karnofsky score, the Chinese the relief of symptoms than the control group, the difference was significant (P<0.05), weekly review of blood results at the end of the observation group were lower than the control group, bone marrow suppression, the difference was significant (P<0.05). With chemotherapy, time and the cumulative dose of doxorubicin increased in the observation group and treatment group had increased serum troponin I, but the increase in the observation group were lower than the time and extent of the treatment group, the difference was significant (P<0.05).Conclusion:Shenqifuzheng injection to relieve adriamycin-induced myocardial damage role, Of chemotherapy-induced myocardial injury has a protective effect, and can improve patient's quality of life, reduce the toxic side effects of chemotherapy,...
Keywords/Search Tags:Shenqifuzheng injection, doxorubicin, heart damage, troponin I
PDF Full Text Request
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