Sugar And Glycoside Synthesis And Structural Characterization Of Metal Complexes

Sugar and glucoside with their important biological activity was one kind of biological molecules that exist broadly in nature. They have the functions of transferring information, shifting energy and transmitting materials while attending life process. As the fast development of molecular biology, especially of cellular biology, more functions of sugar and glucoside have been detected and known to people. The role of anti-tumour and immunity improvement of sugar and glucoside were highlighted, that they have great potential in disease precaution and treatment. In attending many life process, they act not only in their free style, but also in the form of sugar-complex in which sugar or glucoside was linked to other biological molecules. So the research about the complexes of sugar and its derivatives has gotten more and more focus.In this thesis, two metal complexes of sugar-inclusive ligands, ribavirin and inosine, were introduced. The whole thesis consists of two main parts: the first chapter was mainly about the introduction of the progress of research in the field of metal complex of sugar-inclusive ligand. The relative influence of the kinds of sugar-inclusive ligands and metal ions to sugar-complex was also discussed in this part. In the second and third chapter, the synthesis and structure characterization of two sugar-inclusive ligands complexes were introduced. The copper(â…¡) coordination of ribavirin was synthesized by solution volatilization method, while the cadmium(â…¡) coordination polymer of inosine was obtained by thermo-solution method. The two complexes was characterized by means of FT-IR,UV-Vis,fluorescent emission,single crystal X-ray diffraction and TG-DTA.