| This thesis takes the clinical treatment of coronary artery as the object of study. Basing on the clinical effective empirical formula, it complete the new drug development of the empirical formula, consisted by salvia miltiorrhiza , salvia miltiorrhiza etc, and get an exactly effective new drug.First, it determines a rational high quality control method to enforce the quality of the drugs and accomplishes the fingerprints of the original herbs to control the preparing quality from the sources.Secondly,thorough the comparison of finished products, each flavor's HPLC and the ultraviolet spectrums, it primarily discusses the sources and ascriptions of the liyan spray-film dosage's fingerprints;moreover,develop the determination of inorganic with ICP-MS,analyze the elements of heavy metals,macroelements,harmful elements in the preparation.In order to set a good base for the research of drug's second development and the innovate drugs. |
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