.2,6 - Dimethyl Morpholine And Its Derivatives, Synthesis And Process Research

2, 6-dimethyl-morpholine is very important mesial Substance of curative and safeguard reagent of agriculture. In this paper ,with diisopropanolamine containing from 0 to 20 of water for the raw material, 2, 6-dimethyl-morpholine could be synthesized with the overall yield of 88.59%. The reaction conditions were reaction at different temperatures (high temperature and low temperature), concentrated sulfuric acid as the catalyst and solvent. At the same time, we researched the arts and crafts of separate cis-2, 6-dimethyl- morpholine, tran-2, 6-dimethyl-morpholine and water used by rectification, obtaining cis-2,6-dimethyl-morpholine and tran-2, 6-dimethyl-morpholine with 99% pureness. continuity, we also researched the isomerization of cis-2, 6-dimethyl- morpholine, cis-2, 6-dimethyl- morpholine was manufactured by catalytic isomerization of tran-2, 6-dimethyl-morpholine at the optimum condition with different metal complex as catalyst. The optimum yield could reach 50% and best selectivity also could reach 90%.In addition, we were also seeing about the preparation route of the downriver product of 2, 6-dimethyl-morpholine.With 2, 6-dimethyl-morpholine and 1-bromo- isotridecane as raw material ,2, 6-dimethyl-4-isotridecyl-morpholine was produced at 110℃temperature,Na₂CO₃ as the catalyst. The yield could reach 79.32%.