The Synthesis Of The Calixarene Compounds And Applications

Calixarenes are capvity-shipped cyclic molecules made up of phenol units linked by methylene groups.They have higher selectivity compared with cyclodextrins and crown ethers.which are to be counted as the third generation of superamolecules after cyclodextrins and crown ethers.Their functions in the molecular recognition are widely used in modern seperation science.With the view of supermolecular chemistry,we studied the conditions of synthesizing resorcarenes,based on which we derived it with some kinds of method,a few of which were synthesized for the first time,moreover,we studied the chromatographic character of it's derivatives as capillary gas chromatography stationary phase(CGC SP).1. On the basis of the different properties of aliphatic aldehydes and aromatic ones,some syntheses of resorcarenes were attempted under different conditions and a proper synthesis route was foundAccording to this procedure,we synthesized several resorcarenes.2. By the way of derivation of the phenol hydroxy,we obtained alkylate resorcarenes and acetylate resorcarenes3. By the way of direct sulfonation,we obtained a sulfonated resorcarenes which can dissolve in water,and make it possible to expand application of resorcarenes.4. The resorcarenes have been modified by the way of synthesizing Mannich base,we obtained primary amines and secondary amines aminomethylated resorcarenes.Through this way chairl amino acid recommended in the success. For furthure studying the chiral separation of its conquered the foundation5. Reference the syntheses of bridging p-tert-butylcalixarene ,we synthesized bridging resorcarenes.6. Their structure were confirmed by IR 1H-NMR .And the spectroscopicresults proved our synthesis successfully.7. In the thesis alkylate and bridging resorcarenes were used as CGC SP. Their chromatographic character were studied.