Preparation Of Organic - Inorganic Hybrid Nanofiltration Membrane And Its Application In Respect Of Erythromycin Separation

In this paper, the preparation of new organic-inorganic hybrid nanofiltration membranes and their application in erythromycin filtration is presented. Using PVA, tetraethoxy-silicane and nano-silicon dioxide to prepare poly(vinyl alcohol)/SiO2 hybrid nanofiltration membranes by sol-gel and blending method in which KH-560 and DL-malic acid is used as coupling agent and cross-linking agent respectively. The role played by PVA concentration, SiO2 content, coupling agent content and cross-linking condition in the formation of hybrid nanofiltration membranes is investigated. The structure and separation performance of the hybrid nanofiltration membranes are researched systematically. Water flux, erythromycin retention and flux, electrolyte retention and flux are investigated by Quadri-Dynamic Instrument. Mesh size is measured by retention of PEG that has different molecular weights. Microstructure of nanofiltrtion membranes is characterized by FTIR, DSC, TEM and X-ray diffraction. And the heat resistance, acid-base resistance, solvent resistance, swelling and mechanical properties of the hybrid nanofiltration membranes are investigated. Then the effect on filtration and purification of the erythromycin in different operation conditions is discussed.The results presented here offer an outstanding nanfiltration membrane and show that the performance of nanofiltration membrane is improved by hybridization. The tri-cycle erythromycin retention and flux of PVA/SiO2 prepared by sol-gel method are 87.23% and 16 L h-1 m-2 respectively. As a conclusion, the PVA/SiO2 hybrid nanofiltration membrane has a prospected application in extracting erythromycin.